LOINC
Version 2.73

LP15013-3Somatotropin binding proteinActive

Description

LP15013-3   Somatotropin binding protein
Somatotropin binding protein, also known as growth hormone binding protein (GHBP), binds to growth hormone (GH) and functions to increase the half-life of GH by restricting its distribution and preventing its decay. GHBP levels are low in the developing fetus, but increase in the several years after birth to adult levels. There are two forms of GHBP described as low-affinity GHBP and high-affinity GHBP. Both forms bind to growth hormone; 5% of circulating GH is bound to low-affinity GHBP and 45% is bound to high-affinity GHBP. There are several congenital and acquired conditions with altered GHBP levels including Laron-type dwarfism, pygmy dwarfism, malnutrition, obesity, insulin-dependent diabetes mellitus, liver cirrhosis, and renal insufficiency. The most clinically relevant use of GHBP measurements is to confirm suspected Laron dwarfism (where GHBP is absent) or carrier status (GHBP is low).[PMID:7509216] Source: Regenstrief LOINC

Basic Part Properties

Name
Somatotropin binding protein
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
GHBP

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15013-3

Language Variants Get Info

zh-CNChinese (China)
生长激素结合蛋白
Synonyms: GHBP;HGH;人生长激素(Human Growth Hormone,HGH);促生长素结合蛋白;生长激素结合蛋白(Growth Hormone Binding Protein,GHBP,Somatotropin Binding Protein);生长激素结合蛋白(Somatotropin Binding Protein,STBP);生长素结合蛋白;躯体刺激素结合蛋白
nl-NLDutch (Netherlands)
somatotropinebindend eiwit
et-EEEstonian (Estonia)
Somatotropiini siduv proteiin
fr-BEFrench (Belgium)
Protéine de liaison de la Hormone de croissance
Synonyms: Protéine de liaison de la GH
fr-CAFrench (Canada)
Protéine de liaison de la Hormone de croissance
Synonyms: Protéine de liaison de la GH
it-ITItalian (Italy)
Somatotropina, proteina legante
Synonyms: Proteina legante la somatotropina
ru-RURussian (Russian Federation)
Соматотропин связывающий протеин
Synonyms: Соматотропин связывающий белок
es-ESSpanish (Spain)
Proteina de unión a la Somatotropina
Synonyms: Hormona de crecimiento humano
tr-TRTurkish (Turkey)
Somatotropin bağlayıcı protein