LOINC
Version 2.73

LP150268-3t(15;17)(q24.1;q21.1)(PML,RARA)Active

Description

LP150268-3   t(15;17)(q24.1;q21.1)(PML,RARA)
The fusion of promyelocytic leukemia (PML, chromosome 15q24.1) and retinoic acid receptor alpha (RARA, chromosome 17q21.1) genes occurs due to a chromosomal translocation. The fused genes can be detected by various molecular techniques, including FISH and real-time quantitative polymerase chain reaction (RT-qPCR). The test is used to diagnose Acute Promyelocytic Leukemia (APL), detect residual or recurrent APL, and to monitor PML-RARA levels in patients with APL. The assay can be done on whole blood (plasma or cell-based) and bone marrow. Long, variant and/or short isoforms of PML-RARA fusion transcripts may be identified. The ratio of PML-RARA fusion transcript to a control gene (e.g. ABL1) may be reported for positive samples. Source: Regenstrief LOINC

Basic Part Properties

Name
t(15;17)(q24.1;q21.1)(PML,RARA)
Type
Component
Created On
2012-05-21
Construct for LOINC Short Name
t(15;17)(PML,RARA)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP150268-3

Language Variants Get Info

zh-CNChinese (China)
t(15;17)(q24.1;q21.1)(PML,RARA)
Synonyms: 易位(15;17)(q24.1;q21.1)(PML,RARA)
nl-NLDutch (Netherlands)
t(15;17)(q24.1;q21.1)(PML,RARA)
fr-CAFrench (Canada)
t(15;17)(q24.1;q21.1)(PML,RARA)
it-ITItalian (Italy)
t(15;17)(q24.1;q21.1)(PML,RARA)
ru-RURussian (Russian Federation)
t(15;17)(q24.1;q21.1)(PML,RARA)
es-ESSpanish (Spain)
t(15;17)(q24.1;q21.1)(PML,RARA)
tr-TRTurkish (Turkey)
t(15;17)(q24.1;q21.1)(PML,RARA)