LOINC
Version 2.73

LP15038-0PhosphofructokinaseActive

Description

LP15038-0   Phosphofructokinase
Phosphofructokinase (PFK) is a kinase enzyme that phosphorylates fructose-6-phosphate to fructose-1,6-bisphosphate in the glycolytic pathway. PFK exists as a homotetramer in bacteria and mammals (where each monomer possesses 2 similar domains) and as an octomer in yeast (where there are 4 alpha- (PFK1) and 4 beta-chains (PFK2)). Deficiency in PFK leads to glycogenosis type VII (Tarui's disease), an autosomal recessive disorder characterised by severe nausea, vomiting, muscle cramps and myoglobinuria in response to bursts of intense or vigorous exercise. Individuals with PFK deficiency are usually able to relieve symptoms by adjusting activity levels. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Phosphofructokinase (Wikipedia)

Basic Part Properties

Name
Phosphofructokinase
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
PFK

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15038-0

Language Variants Get Info

zh-CNChinese (China)
磷酸果糖激酶
Synonyms: 6-PFK;6-磷酸果糖激酶;PFK
nl-NLDutch (Netherlands)
fosfofructokinase
et-EEEstonian (Estonia)
Fosfofruktokinaas
fr-BEFrench (Belgium)
Phosphofructokinase
fr-CAFrench (Canada)
Phosphofructokinase
it-ITItalian (Italy)
Fosfofruttochinasi
ru-RURussian (Russian Federation)
Фосфофруктокиназа
es-ESSpanish (Spain)
Fosfofructoquinasa
Synonyms: 6-fosfofructoquinasa;Fosfohexoquinasa;PFK
tr-TRTurkish (Turkey)
Fosfofruktokinaz
Synonyms: Fosfohexoquinasa