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Patient's with Th/To autoantibodies immunoprecipitate two small RNAs, known as 7-2 RNA (also RNAase MRP or Th) and 8-2 RNA (also RNAase P, H1 and To). 7-2 RNA is involved in processing of pre-rRNA and 8-2 RNA is involved in maturation of tRNA. Anti-Th/To is frequently detected in the sera of patients with scleroderma and their presence may be associated with a less favorable prognosis. Source: Regenstrief LOINC, PMID: 20175839

Basic Part Properties

Part Display Name
Th-To Ab
Part Type
Component (Describes the core component or analyte measured)
Created On
Construct for LOINC Short Name
Th-To Ab

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Language Variants Get Info

Tag Language Translation
pl-PL Polish (Poland) Th-To Ab
Synonyms: Przeciwciała do antygenów jąderkowych Th-To