LOINC
Version 2.73

LP157222-3Centromere protein AActive

Description

LP157222-3   Centromere protein A
Centromere protein A (CENP-A) is an essential centromere protein encoded by the CENPA gene. Overexpression of CENP-A causes chromosomal aberrations, and depletion of CENP-A promotes apoptosis and induces cell cycle arrest. Overexpression of CENP-A has been associated with high grade cancers and is a prognostic factor for patients with estrogen receptor (ER)-positive breast cancer. Antibodies to CENP-A are associated with scleroderma, systemic sclerosis, CREST syndrome, and other rheumatologic diseases. Source: Regenstrief LOINC

Basic Part Properties

Name
Centromere protein A
Type
Component
Created On
2012-08-22
Construct for LOINC Short Name
CENP A

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP157222-3

Language Variants Get Info

zh-CNChinese (China)
着丝粒蛋白 A
Synonyms: 着丝点蛋白 A;centromere protein A;CENP-A;CENPA
nl-NLDutch (Netherlands)
centromeereiwit A
it-ITItalian (Italy)
Centromero, proteina A
ru-RURussian (Russian Federation)
Центромерный протеин A
es-ESSpanish (Spain)
Proteína A del centrómero (CENP-A)
tr-TRTurkish (Turkey)
Sentromer protein A