LOINC
Version 2.73

LP16198-1MethotrexateActive

Descriptions

LP16198-1   Methotrexate
High-dose methotrexate (MTX) is an antimetabolite drug used in treatment of cancer, and low-dose methotrexate (MTX) is used as a disease modifying antirheumatic drug (DMARD) for long-term treatment of rheumatoid arthritis (RA), psoriasis, and other autoimmune diseases. Methotrexate is a first-line drug in RA treatment. One challenge in the use of the drug is that about 30% of patients do not respond to treatment or experience adverse effects, such as gastrointestinal symptoms, malaise, and psychological complaints. [PMID:20665136] Source: Regenstrief LOINC, PMID: 20665136

LP16198-1   Methotrexate
An anti-neoplastic anti-metabolite with immunosuppressant properties. It inhibits tetrahydrofolate dehydrogenase and prevents the formation of tetrahydrofolate, an essential component of DNA, necessary for synthesis of thymidylate. Source: National Library of Medicine, MeSH 2006

Basic Part Properties

Name
Methotrexate
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
MTX

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16198-1

Language Variants Get Info

zh-CNChinese (China)
氨甲喋呤
Synonyms: C20H22N8O5;甲氨喋呤;氨甲基叶酸;氨甲蝶呤;甲基蝶啶胺;甲基蝶啶胺(化学不孕剂)
nl-NLDutch (Netherlands)
methotrexaat
et-EEEstonian (Estonia)
Metotreksaat
fr-BEFrench (Belgium)
Méthotrexate
fr-CAFrench (Canada)
Méthotrexate
it-ITItalian (Italy)
Metotrexato
ru-RURussian (Russian Federation)
Метотрексат
es-ESSpanish (Spain)
Metotrexato
Synonyms: MTX ®
tr-TRTurkish (Turkey)
Metotreksat