LOINC
Version 2.71

LP16708-7Hepatitis A virusActive

Descriptions

LP16708-7   Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP16708-7   Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported.[PMID:15914081] The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors.[PMID:12186933][PMID:1318940] Source: Regenstrief LOINC

Basic Part Properties

Name
Hepatitis A virus
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
HAV

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16708-7

Language Variants Get Info

zh-CNChinese (China)
甲型肝炎病毒
Synonyms: HAV;Hep A;甲型肝炎;甲肝;甲肝病毒;肝炎病毒 A 型
nl-NLDutch (Netherlands)
Hepatitis A-virus
et-EEEstonian (Estonia)
A-hepatiidi viirus
fr-BEFrench (Belgium)
Virus de l'hépatite A
Synonyms: HVA
fr-CAFrench (Canada)
Virus de l'hépatite A
el-GRGreek (Greece)
Ιός Ηπατίτιδας Α
Synonyms: HAV
it-ITItalian (Italy)
Epatite A, virus
Synonyms: Virus dell''epatite A
ru-RURussian (Russian Federation)
Гепатита А вирус
Synonyms: Virus dell''epatite A
es-ESSpanish (Spain)
Virus de la Hepatitis A
Synonyms: HAV;Hep A
tr-TRTurkish (Turkey)
Hepatit A virüsü
Synonyms: Hep A