LP16714-5HistoneActive
Description
LP16714-5 Histone
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. [PMID:24649358]
Source: Regenstrief LOINC, PMID: 24649358
Basic Part Properties
- Name
- Histone
- Type
- Component
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Histone
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16714-5
Language Variants Get Info
- zh-CNChinese (China)
- 组蛋白
Synonyms: 组朊 - nl-NLDutch (Netherlands)
- histon
- et-EEEstonian (Estonia)
- Histoon
- fr-BEFrench (Belgium)
- Histone
- fr-CAFrench (Canada)
- Histone
- it-ITItalian (Italy)
- Istone
- ru-RURussian (Russian Federation)
- Гистон
- es-ESSpanish (Spain)
- Histona
- tr-TRTurkish (Turkey)
- Histon
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright