LOINC
Version 2.70

LP16750-9Salmonella spActive

Description

LP16750-9   Salmonella sp
Salmonella are gram-negative, flagellated, facultative intracellular, anaerobic bacilli with O, H and Vi surface antigens. Once ingested, Salmonella survives the gastric acid barrier and penetrates the epithelial cells of the small and large intestines. The invasion of the epithelial cells stimulates the release of cytokines and a subsequent inflammatory response leading to diarrhea and possible ulceration of the mucosa.[ NCBI Books: 8435] Antibodies to Salmonella are the body's defense when the bacteria is outside of its host cell which occurs at the initial infection and when the bacillus moves from cell to cell. There is a 10 minute window of opportunity when the Salmonella bacillus leaves the macrophage to invade another. During that time, antibodies and complement work to eradicate the bacilli, but some of the extracellular bacilli will evade attack and enter another host cell. Studies have shown that vaccines play an important role in the fight against typhoid fever. [PMID: 25566248] There are two species of Salmonella: S. enterica and S. bongori. These species can be further subclassified into subspecies and serovars.

Veterinary Medicine:
Salmonella infection is most often caused by the serovars Salmonella choleraesuis, and Salmonella typhimurium and less often by Salmonella derby. Infected pigs can be asymptomatic and become carriers of S. choleraesius. Typically, the bacteria survive in the mesenteric lymph nodes that drain into the intestines, and are not shed in the feces unless the pig is under stress. The carrier state lasts for weeks to months and is self-limiting. Severe infection with S. choleraesius can be serious starting out as septicemia and progressing to pneumonia and enteritis. The infection can spread to various tissues including to the central nervous system leading to meningitis and to the joints where it manifests as arthritis. Severe infections with S. choleraesius occurs at any age, but most often in pigs 12-14 weeks of age.[http://www.thepigsite.com/pighealth/article/357/salmonellosis/] Source: Regenstrief LOINC

Basic Part Properties

Name
Salmonella sp
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
Salmonella

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16750-9

Language Variants Get Info

zh-CNChinese (China)
沙门菌属
Synonyms: 沙门氏菌;沙门氏菌属;沙门菌
nl-NLDutch (Netherlands)
Salmonella sp.
et-EEEstonian (Estonia)
Salmonella sp
fr-BEFrench (Belgium)
Salmonella sp
fr-CAFrench (Canada)
Salmonella sp
it-ITItalian (Italy)
Salmonella sp
ru-RURussian (Russian Federation)
Salmonella sp
es-ESSpanish (Spain)
Salmonella sp
tr-TRTurkish (Turkey)
Salmonella sp