LP16760-8Sjogrens syndrome-A extractable nuclearActive
Description
LP16760-8 Sjogrens syndrome-A extractable nuclear
Sjogren syndrome type A antigen (also known as SS-A, Ro, and E3 ubiquitin-protein ligase TRIM21) and Sjogren syndrome type B antigen (also known as SS-B and Lupus La protein) are nuclear antigens to which autoantibodies develop in autoimmune disorders such as Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). Between 40 and 70% of patients with SS have anti-SSA and/or anti-SSB autoantibodies, and 30-40% and 10-15% of patients with SLE are anti-SSA and anti-SSB positive, respectively. Longitudinal studies have shown that anti-SSA and -SSB antibodies may be present up to 20 years before the clinical onset of disease. SS patients who are anti-SSA and anti-SSB positive may have longer disease duration, parotid gland enlargement, decreased salivary flow, more severe minor salivary gland infiltration and a higher prevalence of extraglandular manifestations. [PMID:27184054]
Source: Regenstrief LOINC, PMID: 27184054
Basic Part Properties
- Name
- Sjogrens syndrome-A extractable nuclear
- Type
- Component
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ENA SS-A
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16760-8
Language Variants Get Info
- zh-CNChinese (China)
- Sjogrens 综合征-a 可提取性核
Synonyms: ENA SS-A;Ro; Ro AB; Ro 抗体; Ro 抗原; Sjogren; Sjogrens 综合征-a ENA; Sjogrens 综合征-a 可提取性核 Ag; Sjogrens 综合征-a 可提取性核抗原; SSA; SS-A; 干燥综合征-a 抗原 - nl-NLDutch (Netherlands)
- SS-A extraheerbare nucleaire
Synonyms: syndroom van Sjögren-A extraheerbare nucleaire - fr-BEFrench (Belgium)
- Syndrome de Sjögren-a nucléaire soluble
- fr-CAFrench (Canada)
- Syndrome de Sjögren-a nucléaire soluble
- el-GRGreek (Greece)
- Αντι-Ro (SSA)
- it-ITItalian (Italy)
- Sjogren, sindrome-nucleare estraibile A
Synonyms: Sindrome di Sjorgen - nucleare estraibile A - ru-RURussian (Russian Federation)
- Шегрена синдром-A экстрагируемый ядерный
Synonyms: Sindrome di Sjorgen - nucleare estraibile A - es-ESSpanish (Spain)
- Antígeno nuclear extraíble Síndrome de Sjogren-A (SS-A)
Synonyms: Anticuerpos Anti-Ro - tr-TRTurkish (Turkey)
- Sjögrens sendromu-A özütlenebilir nükleer
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright