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LP16760-8Sjogrens syndrome-A extractable nuclearActive


LP16760-8   Sjogrens syndrome-A extractable nuclear
Sjogren syndrome type A antigen (also known as SS-A, Ro, and E3 ubiquitin-protein ligase TRIM21) and Sjogren syndrome type B antigen (also known as SS-B and Lupus La protein) are nuclear antigens to which autoantibodies develop in autoimmune disorders such as Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). Between 40 and 70% of patients with SS have anti-SSA and/or anti-SSB autoantibodies, and 30-40% and 10-15% of patients with SLE are anti-SSA and anti-SSB positive, respectively. Longitudinal studies have shown that anti-SSA and -SSB antibodies may be present up to 20 years before the clinical onset of disease. SS patients who are anti-SSA and anti-SSB positive may have longer disease duration, parotid gland enlargement, decreased salivary flow, more severe minor salivary gland infiltration and a higher prevalence of extraglandular manifestations. [PMID:27184054] Source: Regenstrief LOINC, PMID: 27184054

Basic Part Properties

Sjogrens syndrome-A extractable nuclear
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Language Variants Get Info

zh-CNChinese (China)
Sjogrens 综合征-a 可提取性核
Synonyms: ENA SS-A;Ro;Ro AB;Ro 抗体;Ro 抗原;Sjogren;Sjogrens 综合征-a ENA;Sjogrens 综合征-a 可提取性核 Ag;Sjogrens 综合征-a 可提取性核抗原;SSA;SS-A;干燥综合征-a 抗原
nl-NLDutch (Netherlands)
SS-A extraheerbare nucleaire
Synonyms: syndroom van Sjögren-A extraheerbare nucleaire
fr-BEFrench (Belgium)
Syndrome de Sjögren-a nucléaire soluble
fr-CAFrench (Canada)
Syndrome de Sjögren-a nucléaire soluble
el-GRGreek (Greece)
Αντι-Ro (SSA)
it-ITItalian (Italy)
Sjogren, sindrome-nucleare estraibile A
Synonyms: Sindrome di Sjorgen - nucleare estraibile A
ru-RURussian (Russian Federation)
Шегрена синдром-A экстрагируемый ядерный
Synonyms: Sindrome di Sjorgen - nucleare estraibile A
es-ESSpanish (Spain)
Antígeno nuclear extraíble Síndrome de Sjogren-A (SS-A)
Synonyms: Anticuerpos Anti-Ro
tr-TRTurkish (Turkey)
Sjögrens sendromu-A özütlenebilir nükleer