LOINC
Version 2.73

LP16761-6Sjogrens syndrome-B extractable nuclearActive

Description

LP16761-6   Sjogrens syndrome-B extractable nuclear
Sjogren syndrome type A antigen (also known as SS-A, Ro, and E3 ubiquitin-protein ligase TRIM21) and Sjogren syndrome type B antigen (also known as SS-B and Lupus La protein) are nuclear antigens to which autoantibodies develop in autoimmune disorders such as Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). Between 40 and 70% of patients with SS have anti-SSA and/or anti-SSB autoantibodies, and 30-40% and 10-15% of patients with SLE are anti-SSA and anti-SSB positive, respectively. Longitudinal studies have shown that anti-SSA and -SSB antibodies may be present up to 20 years before the clinical onset of disease. SS patients who are anti-SSA and anti-SSB positive may have longer disease duration, parotid gland enlargement, decreased salivary flow, more severe minor salivary gland infiltration and a higher prevalence of extraglandular manifestations. [PMID:27184054] Source: Regenstrief LOINC, PMID: 27184054

Basic Part Properties

Name
Sjogrens syndrome-B extractable nuclear
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
ENA SS-B

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16761-6

Language Variants Get Info

zh-CNChinese (China)
Sjogrens 综合征-b 可提取性核
Synonyms: Sjogrens 综合征-b ENA;Sjogrens 综合征-b ENA Ag;Sjogrens 综合征-b ENA 抗原;Sjogrens 综合征-b 可提取性核 Ag;Sjogrens 综合征-b 可提取性核抗原;SSB;SS-B;SSB Ag;SS-B Ag;SSB 抗原;SS-B 抗原;干燥综合征-b Ag;干燥综合征-b 抗原
nl-NLDutch (Netherlands)
SS-B extraheerbare nucleaire
Synonyms: syndroom van Sjögren-B extraheerbare nucleaire
fr-BEFrench (Belgium)
Syndrome de Sjögren-b nucléaire soluble
fr-CAFrench (Canada)
Syndrome de Sjögren-b nucléaire soluble
el-GRGreek (Greece)
Αντι-La (SSB)
it-ITItalian (Italy)
Sjogren, sindrome-nucleare estraibile B
Synonyms: Sindrome di Sjorgen - nucleare estraibile B
ru-RURussian (Russian Federation)
Шегрена синдром-B экстрагируемый ядерный
Synonyms: Sindrome di Sjorgen - nucleare estraibile B
es-ESSpanish (Spain)
Antígeno nuclear extraíble Síndrome de Sjogren-B (SS-B)
Synonyms: Anticuerpos Anti-Ha
tr-TRTurkish (Turkey)
Sjogrens sendromu-B özütlenebilir nükleer