LP16761-6Sjogrens syndrome-B extractable nuclearActive

Description

LP16761-6   Sjogrens syndrome-B extractable nuclear
Sjogren syndrome type A antigen (also known as SS-A, Ro, and E3 ubiquitin-protein ligase TRIM21) and Sjogren syndrome type B antigen (also known as SS-B and Lupus La protein) are nuclear antigens to which autoantibodies develop in autoimmune disorders such as Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). Between 40 and 70% of patients with SS have anti-SSA and/or anti-SSB autoantibodies, and 30-40% and 10-15% of patients with SLE are anti-SSA and anti-SSB positive, respectively. Longitudinal studies have shown that anti-SSA and -SSB antibodies may be present up to 20 years before the clinical onset of disease. SS patients who are anti-SSA and anti-SSB positive may have longer disease duration, parotid gland enlargement, decreased salivary flow, more severe minor salivary gland infiltration and a higher prevalence of extraglandular manifestations. [PMID:27184054] Source: Regenstrief LOINC, PMID: 27184054

Basic Part Properties

Name

Sjogrens syndrome-B extractable nuclear

Type

Component

Created On

2000-05-04

Construct for LOINC Short Name

ENA SS-B

LOINC FHIR^® API Example - CodeSystem Request Get Info

Language Variants Get Info

zh-CNChinese (China)

Sjogrens 综合征-b 可提取性核
Synonyms: Sjogrens 综合征-b ENA;Sjogrens 综合征-b ENA Ag;Sjogrens 综合征-b ENA 抗原;Sjogrens 综合征-b 可提取性核 Ag;Sjogrens 综合征-b 可提取性核抗原;SSB;SS-B;SSB Ag;SS-B Ag;SSB 抗原;SS-B 抗原;干燥综合征-b Ag;干燥综合征-b 抗原

nl-NLDutch (Netherlands)

SS-B extraheerbare nucleaire
Synonyms: syndroom van Sjögren-B extraheerbare nucleaire

fr-BEFrench (Belgium)

Syndrome de Sjögren-b nucléaire soluble

fr-CAFrench (Canada)

Syndrome de Sjögren-b nucléaire soluble

el-GRGreek (Greece)

Αντι-La (SSB)

it-ITItalian (Italy)

Sjogren, sindrome-nucleare estraibile B
Synonyms: Sindrome di Sjorgen - nucleare estraibile B

ru-RURussian (Russian Federation)

Шегрена синдром-B экстрагируемый ядерный
Synonyms: Sindrome di Sjorgen - nucleare estraibile B

es-ESSpanish (Spain)

Antígeno nuclear extraíble Síndrome de Sjogren-B (SS-B)
Synonyms: Anticuerpos Anti-Ha

tr-TRTurkish (Turkey)

Sjogrens sendromu-B özütlenebilir nükleer

LOINC Copyright

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