LP173611-7MesothelinActive
Description
LP173611-7 Mesothelin
Mesothelin, or MSLN, is a40 kDa protein that is encoded by the MSLN gene. It is present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The protein was first identified by its reactivity with monoclonal antibody K1. Subsequent cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.
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Source: Wikipedia, Mesothelin
Basic Part Properties
- Name
- Mesothelin
- Type
- Component
- Created On
- 2013-07-31
- Construct for LOINC Short Name
- Mesothelin
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP173611-7
Language Variants Get Info
- zh-CNChinese (China)
- 间皮素
Synonyms: 间皮蛋白 - nl-NLDutch (Netherlands)
- mesotheline
- it-ITItalian (Italy)
- Mesotelina
- ru-RURussian (Russian Federation)
- Мезотелин
- es-ESSpanish (Spain)
- Mesotelina
- tr-TRTurkish (Turkey)
- Mezsotelin
LOINC Copyright
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