LOINC
Version 2.73

LP173611-7MesothelinActive

Description

LP173611-7   Mesothelin
Mesothelin, or MSLN, is a40 kDa protein that is encoded by the MSLN gene. It is present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The protein was first identified by its reactivity with monoclonal antibody K1. Subsequent cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mesothelin

Basic Part Properties

Name
Mesothelin
Type
Component
Created On
2013-07-31
Construct for LOINC Short Name
Mesothelin

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP173611-7

Language Variants Get Info

zh-CNChinese (China)
间皮素
Synonyms: 间皮蛋白
nl-NLDutch (Netherlands)
mesotheline
it-ITItalian (Italy)
Mesotelina
ru-RURussian (Russian Federation)
Мезотелин
es-ESSpanish (Spain)
Mesotelina
tr-TRTurkish (Turkey)
Mezsotelin