LOINC
Version 2.73

LP18213-6Myelin associated glycoproteinActive

Description

LP18213-6   Myelin associated glycoprotein
Myelin associated glycoprotein (MAG) is a 100 kDa transmembrane glycoprotein found in the periaxonal membranes of Schwann cells and oligodendrocytes of myelin sheaths. Despite the fact that MAG is a known white matter inhibitor of axonal regeneration and as a receptor for IgM antibodies that demyelinates peripheral nerves, it has important roles that promote normal formation and maintenance of myelinated axons. There are two apparent functions of MAG which are to act as a ligand for an axonal receptor which maintains myelinated axons, and to act as an axonal signal receptor that promotes differentiation, maintenance, and survival of oligodendrocytes. MAG shares an epitope with other glyoconjugates that is the target protein in autoimmune peripheral neuropathy, that is associated with IgM gammopathy which causes the death of oligodendrocytes that is seen in multiple sclerosis.[PMID:17241126] Source: Regenstrief LOINC

Basic Part Properties

Name
Myelin associated glycoprotein
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
MAG

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP18213-6

Language Variants Get Info

zh-CNChinese (China)
髓磷脂相关糖蛋白
Synonyms: MAG;髓磷脂相关糖蛋白(Myelin Associated Glycoprotein,MAG)
nl-NLDutch (Netherlands)
myeline-geassocieerd glycoproteïne
fr-BEFrench (Belgium)
Glycoprotéine associée à la myéline
fr-CAFrench (Canada)
Glycoprotéine associée à la myéline
it-ITItalian (Italy)
Mielina, glicoproteina associata
Synonyms: Glicoproteina associata alla mielina
ru-RURussian (Russian Federation)
Миелин ассоциированный гликопротеин
Synonyms: Миелин-ассоциированный гликопротеин
es-ESSpanish (Spain)
Glicoproteína asociada a la mielina
Synonyms: Миелин-ассоциированный гликопротеин
tr-TRTurkish (Turkey)
Miyelinle ilişkili glikoprotein