LOINC
Version 2.73

LP182297-4Cocaine+MetabolitesActive

Description

LP182297-4   Cocaine+Metabolites
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium.[PMID:8761012] Source: Regenstrief LOINC

Basic Part Properties

Name
Cocaine+Metabolites
Type
Component
Created On
2014-01-02
Construct for LOINC Short Name
Coc+Met

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP182297-4

Language Variants Get Info

zh-CNChinese (China)
可卡因+代谢产物
Synonyms: 可卡因+代谢物; 古柯碱+代谢产物;柯卡因+代谢产物;古柯硷+代谢产物
nl-NLDutch (Netherlands)
cocaïne + metabolieten
it-ITItalian (Italy)
Cocaina+Metaboliti
ru-RURussian (Russian Federation)
Кокаин+Метаболиты
es-ESSpanish (Spain)
Cocaina+Metabolitos
tr-TRTurkish (Turkey)
Kokain+Metabolitleri