LOINC
Version 2.67

LP18868-7AmphetamineActive

Description

LP18868-7   Amphetamine
Amphetamine (AMPH) is a drug that stimulates both the central and peripheral nervous systems and is used to treat attention-deficit/hyperactivity disorder, narcolepsy and obesity. [PMID: 17209801] AMPH increases extracellular monoamine neurotransmitters in the brain including dopamine, serotonin and norepinephrine. AMPH promotes presynaptic release of the neurotransmitters rather than blocking their re-uptake. Physiological responses to AMPH use include increased blood pressure, increased heart rate, increased body temperature, relaxed bronchial muscle and depressed appetite. Abuse of AMPH can cause powerful psychological dependence, tolerance, mild physical dependence associated with tachycardia, restlessness, irritability, insomnia, personality changes and an intense form of chronic intoxication psychosis similar to schizophrenia. Long-term users of AMPH can experience depression, impaired memory and motor skills most likely due to a drop in dopamine transporters and damage to dopaminergic and serotonergic neurons. Excretion of AMPH is in the urine and the rate of elimination is dependent on the pH of the urine. Urine with an alkaline pH has an excretion rate of 18-34 hours while that of acid urine is 7-14 hours.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns) Source: Regenstrief LOINC

Basic Part Properties

Name
Amphetamine
Type
Component
Created On
2000-05-04
Construct for LOINC Short Name
Amphet

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP18868-7

Language Variants Get Info

zh-CNChinese (CHINA)
苯丙胺
Synonyms: C9H13N;安非他明;苯异丙胺;苯齐巨林
nl-NLDutch (NETHERLANDS)
amfetamine
et-EEEstonian (ESTONIA)
Amfetamiin
fr-BEFrench (BELGIUM)
Amphétamine
fr-CAFrench (CANADA)
Amphétamine
it-ITItalian (ITALY)
Anfetamina
ru-RURussian (RUSSIAN FEDERATION)
Амфетамин
es-ESSpanish (SPAIN)
Anfetamina
Synonyms: Amph;Amphet;Amphetam;Ampht;Anfetaminas;Speed
tr-TRTurkish (TURKEY)
Amfetamin
Synonyms: Amphet