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LP190786-6Toscana virusActive


LP190786-6   Toscana virus
Toscana virus (TOSV) was identified in 1971 in central Italy from sandflies Phlebotomus perniciosus and Phlebotomus perfiliewi [PMID: 24175218] . TOSV belongs to the family Phenuiviridae, genus Phlebovirus [NCBI: 11590)]. TOSV is a serotype of the species Sandfly fever Naples virus [PMID: 24175218] . TOSV is the only neurotropic sandfly phlebovirus typically causing meningitis and encephalitis. Additional neuroinvasive manifestations such as Guillain-Barré syndrome, hydrocephalus, myositis, fasciitis, polymyeloradiculopathy, deafness, and facial paralysis, have been reported. Toscana virus broadly circulates in in European Mediterranean basin and Northern Africa [PMID: 32878929] . Source: Regenstrief LOINC

LP190786-6   Toscana virus
The Toscana virus (TOSV) belongs to the Bunyaviridae family whose genome is made of three negative single-stranded RNA segments. There are two genotypes of TOSV: A, found mainly in Italy, and B, occurring mainly in Spain. The distribution of the two genotypes may indicate the involvement of different vectors. Infection by TOSV is most prevalent in Italy and Spain in the summer months, though the geographical region where TOSV is expanding includes other countries in the Mediterranean basin. TOSV is transmitted to humans by the Phlebotomus species of sandflies. Though the animal reservoir has not been identified, TOSV has been isolated from the brain of a bat, which raises the question of it possibly being a host to the virus. TOSV causes aseptic meningitis in 95% of the people it infects, meningoencephalitis in 4.5% of those infected, and an influenza-like illness in the remaining .5% who are infected. Recently, unusual symptoms associated with TOSV have included ischemic complications and hydrocephalus. TOSV is emerging as an important pathogen as its distribution increases due to changes in the climate, globalization and habitat modification. Other than supportive therapy, there is no treatment for infection with TOSV. [PMID: 20517492] Source: Regenstrief LOINC

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Toscana virus
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Language Variants Get Info

zh-CNChinese (China)
Synonyms: Toscana 病毒
nl-NLDutch (Netherlands)
Toscana virus
it-ITItalian (Italy)
Virus Toscana
es-ESSpanish (Spain)
Virus Toscana
tr-TRTurkish (Turkey)
Toscana virüs