LP200416-8t(2;3)(q13;p25)(PAX8,
Description
LP200416-8 t(2;3)(q13;p25)(PAX8,PPARG)
The PAX8/PPARG (paired box 8/peroxisome proliferator-activated receptor gamma) gene rearrangement is created by a translocation between chromosome arms 2q and 3p where the entire coding region of the PPARG transcription factor gene is fused with the first 8 to 10 exons of the PAX8 gene.[PMID:10958784] Translocations of the PAX8/PPARG genes play a role in the pathogenesis of some follicular thyroid carcinomas and follicular-variant papillary thyroid carcinoma.[PMID:20056739] Several testing methods are used to detect the rearrangement, including fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and reverse-transcription PCR (RT-PCR).
Source: Regenstrief LOINC
Basic Part Properties
- Name
- t(2;3)(q13;p25)(PAX8,PPARG)
- Type
- Component
- Created On
- 2015-09-21
- Construct for LOINC Short Name
- t(2;3)(PAX8,PPARG)
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP200416-8
Language Variants Get Info
- zh-CNChinese (China)
- t(2;
3)(q13; p25)(PAX8,PPARG)
Synonyms: 易位(2;3)(q13; p25)(PAX8,PPARG) - nl-NLDutch (Netherlands)
- t(2;
3)(q13; p25)(PAX8,PPARG) - it-ITItalian (Italy)
- t(2;
3)(q13; p25)(PAX8,PPARG) - es-ESSpanish (Spain)
- t(2;
3)(q13; p25)(PAX8,PPARG) - tr-TRTurkish (Turkey)
- t(2;
3)(q13; p25)(PAX8,PPARG)
LOINC Copyright
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