LOINC
Version 2.72

LP200416-8t(2;3)(q13;p25)(PAX8,PPARG)Active

Description

LP200416-8   t(2;3)(q13;p25)(PAX8,PPARG)
The PAX8/PPARG (paired box 8/peroxisome proliferator-activated receptor gamma) gene rearrangement is created by a translocation between chromosome arms 2q and 3p where the entire coding region of the PPARG transcription factor gene is fused with the first 8 to 10 exons of the PAX8 gene.[PMID:10958784] Translocations of the PAX8/PPARG genes play a role in the pathogenesis of some follicular thyroid carcinomas and follicular-variant papillary thyroid carcinoma.[PMID:20056739] Several testing methods are used to detect the rearrangement, including fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and reverse-transcription PCR (RT-PCR). Source: Regenstrief LOINC

Basic Part Properties

Name
t(2;3)(q13;p25)(PAX8,PPARG)
Type
Component
Created On
2015-09-21
Construct for LOINC Short Name
t(2;3)(PAX8,PPARG)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP200416-8

Language Variants Get Info

zh-CNChinese (China)
t(2;3)(q13;p25)(PAX8,PPARG)
Synonyms: 易位(2;3)(q13;p25)(PAX8,PPARG)
nl-NLDutch (Netherlands)
t(2;3)(q13;p25)(PAX8,PPARG)
it-ITItalian (Italy)
t(2;3)(q13;p25)(PAX8,PPARG)
es-ESSpanish (Spain)
t(2;3)(q13;p25)(PAX8,PPARG)
tr-TRTurkish (Turkey)
t(2;3)(q13;p25)(PAX8,PPARG)