LOINC
Version 2.70

LP21132-3Chikungunya virusActive

Descriptions

LP21132-3   Chikungunya virus
A species of ALPHAVIRUS causing an acute dengue-like fever. Source: National Library of Medicine, MeSH 2006

LP21132-3   Chikungunya virus
Chikungunya virus (CHIKV) belongs to the mosquito-borne alphavirus genus, in the family Togaviridae, and was first observed in epidemic form in Africa. Serologically, CHIKV belongs to the Semliki Forest (SF) subgroup of alphaviruses. Infection in humans is characterized by rash, high fever and, its hallmark feature, severe arthritis that can persist for years. CHIKV is a small, spherical, enveloped, positive-strand RNA virus. The virion consists of an envelope and a nucleocapsid. The envelope glycoproteins of alphaviruses are the distinguishing factors for testing. The CHIKV genome encodes for two polyproteins; the non-structural polyprotein consisting of four proteins (nsP1, nsP2, nsP3 and nsP4) and the structural polyprotein consisting of five proteins (Capsid, E3, E2, 6K and E1). CHIKV has spikes on the virion surface that are each formed by three E1-E2 heterodimers, where the E1 glycoproteins mediate fusion and E2 glycoproteins interact with the host receptor. [PMID: 20111039]
CHIKV can be detected between the first and fourth day of infection (the acute phase) using PCR or virus cultivation, and virus-specific IgM and IgG antibodies can be detected during the 8th to the 10th day of infection. Antibody investigation should be performed using serum samples from the acute and convalescent stage. Source: Regenstrief LOINC

Basic Part Properties

Name
Chikungunya virus
Type
Component
Created On
2000-10-16
Construct for LOINC Short Name
CHIKV

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP21132-3

Language Variants Get Info

zh-CNChinese (China)
基孔肯亚病毒
Synonyms: 奇昆古尼亚病毒;基孔肯雅病毒;CHIKV
nl-NLDutch (Netherlands)
Chikungunya-virus
fr-BEFrench (Belgium)
Virus Chikungunya
fr-CAFrench (Canada)
Virus Chikungunya
it-ITItalian (Italy)
Chikungunya virus
Synonyms: CHIK
ru-RURussian (Russian Federation)
Чикунгунья вирус
es-ESSpanish (Spain)
Virus Chikungunya
Synonyms: CHIKV
tr-TRTurkish (Turkey)
Chikungunya virus