LP220407-3TitinActive
Description
LP220407-3 Titin
The titin protein plays a role in the assembly and functioning of striated muscles by connecting individual microfilaments, and may play a role in chromosome condensation and segregation during mitosis in non-muscle cells. [UniProt: Q8WZ42] Myasthenia gravis (MG) is an autoimmune disease mediated by antibodies against the acetylcholine receptor (AChR) in the postsynaptic membrane of the motor end plate, but antibodies against other targets, including titin, also play an important role. Anti-titin autoantibodies are also a sensitive marker for thymoma, which is often associated with MG, especially in patients with MG who are younger than 60 years old. [PMID: 11405802]
Source: Regenstrief LOINC, PMID: 11405802
Basic Part Properties
- Name
- Titin
- Type
- Component
- Created On
- 2016-07-07
- Construct for LOINC Short Name
- Titin
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP220407-3
Language Variants Get Info
- zh-CNChinese (CHINA)
- 肌巨蛋白
Synonyms: 肌联蛋白;肌聚蛋白; 肌弹力蛋白 - it-ITItalian (ITALY)
- Titina
- es-ESSpanish (SPAIN)
- Titina
LOINC Copyright
Copyright © 2019 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright