LOINC
Version 2.67

LP220413-1TIF1-gammaActive

Description

LP220413-1   TIF1-gamma
Transcriptional intermediary factor 1-gamma (TIF1-gamma or E3 ubiquitin-protein ligase TRIM33), induces inactivation of the SMAD4 protein, which promotes cell growth (including malignant tumours) by inhibiting the anti-proliferative effects of TGF-beta. Anti-TIF1-gamma autoantibodies have been associated with adult- and juvenile-onset dermatomyositis (DM), and particularly with cancer-associated DM. [PMID: 20501546] Source: Regenstrief LOINC, PMID: 20501546

Basic Part Properties

Name
TIF1-gamma
Type
Component
Created On
2016-07-07
Construct for LOINC Short Name
TIF1-gamma

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP220413-1

Language Variants Get Info

zh-CNChinese (CHINA)
TIF1-gamma
Synonyms: TIF1-γ;TIF1-gamma;转录中介因子 1-γ;转录中介因子 1-gamma;Transcriptional intermediary factor 1-gamma;E3 泛素连接酶 TRIM33;E3 ubiquitin-protein ligase TRIM33
nl-NLDutch (NETHERLANDS)
TIF1-gamma
it-ITItalian (ITALY)
TIF1-gamma
es-ESSpanish (SPAIN)
TIF1-gamma