LOINC
Version 2.68

LP229975-0AMPAR2Active

Description

LP229975-0   Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor 1 (AMPAR1) and AMPA receptor 2 (AMPAR2) antibodies target the AMPA receptor, an ionotropic glutamate receptor and key excitatory neurotransmitter. AMPA receptors are comprised of different combinations of four glutamate receptor subunits called GluA1–GluA4 (also known as GluR1–GluR4 and GluR-A to GluR-D). They are vital for brain development and function, such as memory and cognitive development. Detection of antineuronal autoantibodies against AMPA receptors aids in the diagnosis of autoimmune encephalopathies, especially limbic encephalitis, and related conditions.[PMCID: PMC4478035] The presence of AMPA antibodies may also indicate an undiscovered tumor in the thymus, lung or breast. [PMID: 23983888] The neurological symptoms associated with AMPA receptor 1 antibodies include altered mental status, convulsions, memory loss amnesia, auditory hallucinations, limbic encephalitis, abnormal behavior, schizophrenia, dizziness and hyperthermia. The neurological symptoms associated with AMPA receptor 2 antibodies include seizures, short-term memory loss, limbic encephalitis, altered mental status, chorea and facial dyskinesia. [PMID: 24707504] Source: Regenstrief LOINC

Basic Part Properties

Name
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor 2
Type
Component
Created On
2016-09-14
Construct for LOINC Short Name
AMPAR2

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP229975-0

Language Variants Get Info

zh-CNChinese (CHINA)
Alpha-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体 2
Synonyms: Alpha-氨基-3-羟基-5-甲基-4-异恶唑丙酸受体 2;α-氨基-3-羟基-5-甲基-4-异唑丙酸受体 2;α–氨基–3–羟基–5–甲基–4–异唑丙酸受体 2;AMPAR2
nl-NLDutch (NETHERLANDS)
alfa-amino-3-hydroxy-5-methyl-4-isoxazolpropionaatreceptor 2
it-ITItalian (ITALY)
Recettore tipo 2 per alfa-amino-3-idrossi-5metil-4-isoxazolepropionato
Synonyms: AMPAR2
es-ESSpanish (SPAIN)
Receptor 2 de Alfa-amino-3-hidroxi-5-metil-4-isoxazolepropionato