LOINC
Version 2.67

LP230275-2SUMO-activating enzyme subunit 1 IgGActive

Description

LP230275-2   SUMO-activating enzyme subunit 1 Ab.IgG
Small ubiquitin-like modifier 1 (SUMO-1) is one of four enzymes in the SUMO family which plays a key role in posttranslational protein modification. SUMO-1 consists of the SUMO-1 activating enzyme A subunit (SAE1) and the SUMO-1 activating enzyme B subunit (SAE2), which have molecular weights of 40kD and 90kD, respectively. The SUMO family has been associated with diseases such as rheumatoid arthritis and primary biliary cirrhosis. SAE1 and SAE2 have been found in patients with dermatomyositis (DM) associated with widespread skin involvement, dysphagia, and interstitial pneumonia. Patients with DM without these specific associated symptoms are typically anti-SAE antibody negative. [PMID: 17763420] Source: Regenstrief LOINC, PMID: 17763420

Basic Part Properties

Name
SUMO-activating enzyme subunit 1 Ab.IgG
Type
Component
Created On
2016-09-29

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP230275-2