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LP248274-5Bacterial carbapenem resistance bla OXA-48-like geneActive


LP248274-5   Bacterial carbapenem resistance blaOXA-48-like gene
The existence of OXA-48 like class D beta-lactamases has been increasing in enterobacter species organisms. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. [PMID:24696435]. The OXA-48 like class D beta-lactamase enzymes are highly resistant to penicillins and beta lactamase inhibitors and show a low resistance to carbapenems. These varied OXA-48-like beta-lactamases have been identified worldwide, including OXA-48-like producing Klebsiella pneumoniae with resistance to multiple drugs that emerged in Jordanian hospitals. Reports have shown that organisms producing OXA-48 like enzymes are either not resistant to broad-spectrum cephalosporins or show a decreased susceptibility to carbapenemase drugs. Identifying them can be a challenge. Screening and detection is required to prevent and control dissemination.[PMID:22499996] [PMID:26993738] Source: Regenstrief LOINC

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Bacterial carbapenem resistance blaOXA-48-like gene
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zh-CNChinese (China)
细菌碳青霉烯类耐药 blaOXA-48-样基因
Synonyms: 细菌细菌碳青霉烯类(碳青霉烯类抗生素、碳青霉烯)耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) blaOXA-48-样基因
nl-NLDutch (Netherlands)
bacteriële carbapenemresistentie blaOXA-48-like gen
it-ITItalian (Italy)
Resistenza batterica ai carbapenemici, gene blaOXA-48-like
Synonyms: Gene blaOXA-48-like di resistenza batterica ai carbapenemi
es-ESSpanish (Spain)
gen bacteriano similar blaOXA-48 resistente a carbapenem