LP248274-5Bacterial carbapenem resistance bla OXA-48-like geneActive
Description
LP248274-5 Bacterial carbapenem resistance blaOXA-48-like gene
The existence of OXA-48 like class D beta-lactamases has been increasing in enterobacter species organisms. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. [PMID:24696435]. The OXA-48 like class D beta-lactamase enzymes are highly resistant to penicillins and beta lactamase inhibitors and show a low resistance to carbapenems. These varied OXA-48-like beta-lactamases have been identified worldwide, including OXA-48-like producing Klebsiella pneumoniae with resistance to multiple drugs that emerged in Jordanian hospitals. Reports have shown that organisms producing OXA-48 like enzymes are either not resistant to broad-spectrum cephalosporins or show a decreased susceptibility to carbapenemase drugs. Identifying them can be a challenge. Screening and detection is required to prevent and control dissemination.[PMID:22499996] [PMID:26993738]
Source: Regenstrief LOINC
Basic Part Properties
- Name
- Bacterial carbapenem resistance blaOXA-48-like gene
- Type
- Component
- Created On
- 2017-02-20
- Construct for LOINC Short Name
- blaOXA-48-like
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP248274-5
Language Variants Get Info
- zh-CNChinese (China)
- 细菌碳青霉烯类耐药 blaOXA-48-样基因
Synonyms: 细菌细菌碳青霉烯类(碳青霉烯类抗生素、碳青霉烯)耐药(抗性、 耐性、 耐药性、 抗药、 抗药性、 耐受、 耐药型) blaOXA-48-样基因 - nl-NLDutch (Netherlands)
- bacteriële carbapenemresistentie blaOXA-48-like gen
- it-ITItalian (Italy)
- Resistenza batterica ai carbapenemici, gene blaOXA-48-like
Synonyms: Gene blaOXA-48-like di resistenza batterica ai carbapenemi - es-ESSpanish (Spain)
- gen bacteriano similar blaOXA-48 resistente a carbapenem
LOINC Copyright
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