LOINC
Version 2.73

LP248280-2Bacterial beta-lactam resistance ESBL blaCTX-M-9 Group geneActive

Description

LP248280-2   Bacterial beta-lactam resistance ESBL blaCTX-M-9 Group gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. [https://www.uptodate.com/contents/extended-spectrum-beta-lactamases] Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. These enzymes are classified in five major phylogenetic groups based on their gene sequences: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25; two additional groups have been reported recently: CTX-M-74 and CTX-M-75. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. [PMID:25234380] The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1. Source: Regenstrief LOINC

Basic Part Properties

Name
Bacterial beta-lactam resistance ESBL blaCTX-M-9 Group gene
Type
Component
Created On
2017-02-20
Construct for LOINC Short Name
ESBL blaCTX-M9 Grp gene

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https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP248280-2

Language Variants Get Info

zh-CNChinese (China)
细菌 beta-内酰胺耐药 ESBL blaCTX-M-9 组基因
Synonyms: 细菌 beta-内酰胺(β-内酰胺)耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) ESBL(超广谱β-内酰胺酶) blaCTX-M-9 组基因
nl-NLDutch (Netherlands)
bacteriële bètalactamresistentie ESBL blaCTX-M-9 groep gen
it-ITItalian (Italy)
Resistenza batterica beta-lactamica, gene Gruppo ESBL blaCTX-M-9
Synonyms: Gene Gruppo ESBL blaCTX-M-9 di resistenza batteric
es-ESSpanish (Spain)
Grupo genes bacterianos ESBL blaCTX-M-9 resistente a beta-lactámicos