Version 2.77

Description

The Escherichic coli (EC) K99 fimbrial protein requires eight gene products that are encoded by eight contiguous genes (fanA through fanH) before it can be biosynthesized. The pilus K99 is often present on enterotoxigenic Escherichia coli (ETEC) found in the intestines of neonatal pigs, causing severe diarrheal disease. PMID: 7558331 Escherichia coli (EC) is a gram-negative, flagellated, rod-shaped bacterium that is composed of a stable core set of genes, and another more fluid set of genes that includes the virulence genes. These virulence genes increase the pathogenicity of EC and encode heat-stable and heat-labile enterotoxins, Shiga toxin 2e, and fimbria, including the F5 fimbria (also known as K99). The virulence genes can be transferred laterally between dividing EC. PMID: 7021219[https://vetmed.iastate.edu/vdpam/FSVD/swine/index-diseases/colibacillosis] E. coli infection in pigs causes post-weaning diarrhea (PWD) which leads to watery diarrhea, dehydration, loss of body weight, and occasionally death. EC adheres to the small intestine using adhesin factors, and produces one or more exotoxins that induce fluid and electrolyte secretion. PMID: 7648523 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Escherichia coli K99 DNA
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-07-14
Construct for LOINC Short Name
EC K99 DNA

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