LOINC
Version 2.73

LP266717-0FluoroquinoloneActive

Description

LP266717-0   Fluoroquinolone
Fluorquinolones are among most beneficial drugs used to treat multi-drug resistant Mycobacterium tuberculosis (MDR-TB) infections. The fluorquinolones affect the activity of DNA gyrase by reducing the cell's ability for DNA replication and transcription. DNA gyrase in Mycobacterium tuberculosis (TB) is made of two subunits that are encoded by gyrA and gyrB. Mutations in the gyrA quinolone resistance-determining region (QRDR) are responsible for causing most of the drug resistance of TB to the fluoroquinolones. The gyrB mutations have a much smaller impact on TB resistance to the fluoroquinolones.[PMID:26763957] Source: Regenstrief LOINC

Basic Part Properties

Name
Fluoroquinolone
Type
Component
Created On
2018-03-27
Construct for LOINC Short Name
FLQ

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP266717-0

Language Variants Get Info

zh-CNChinese (China)
氟喹诺酮
Synonyms: 氟喹诺酮类抗生素;氟喹诺酮类药物
nl-NLDutch (Netherlands)
fluorchinolon
it-ITItalian (Italy)
Fluorochinolone
es-ESSpanish (Spain)
Fluoroquinolona