LOINC
Version 2.73

LP29041-8Cortisol FreeActive

Descriptions

LP29041-8   Cortisol.free
Free cortisol levels evaluate adrenal cortical function, especially hyperfunction. Urinary cortisol reflects the portion of serum-free cortisol filtered by the kidney. Urinary free cortisol is a better reflection of cortisol secretion than a single serum specimen. Increased urinary free cortisol in an unstressed patient is diagnostic for Cushing syndrome. Increases occur also in pregnancy and with oral contraceptives. Source: Regenstrief Institute

LP29041-8   Cortisol.free
Cortisol is a glucocorticoid produced in the adrenal cortex. A synthetic version of this same chemical is called hydrocortisone and manufactured as medication. Cortisol is not to be confused with cortisone, a closely related compound with much less (PubChem calls it "inactive") biologic activity. Cortisone is also offered as a drug, and it is converted to cortisol (the active form) in the liver. They both have a circadian rhythm with peak in the AM (around 8AM) and trough in the evening (around midnight), but this shifts according to sleep habits (work shifts). The morning measurement, which should be high, is most useful for diagnosing Addison's disease (too little cortisol) and the evening measurement, which should be low, is the most useful for diagnosing Cushing's disease (too much cortisol). Salivary cortisol may be a more sensitive measure than serum or plasma. Source: Regenstrief Help

Basic Part Properties

Name
Cortisol.free
Type
Component
Created On
2002-06-18
Construct for LOINC Short Name
Cortis F

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP29041-8

Language Variants Get Info

zh-CNChinese (China)
皮质醇.游离型
Synonyms: 皮质醇（可的索、考的索）.游离型;游离型皮质醇;游离皮质醇;皮质醇.游离
nl-NLDutch (Netherlands)
cortisol.vrij
et-EEEstonian (Estonia)
Kortisool.vaba
fr-BEFrench (Belgium)
Cortisol.libre
fr-CAFrench (Canada)
Cortisol.libre
it-ITItalian (Italy)
Cortisolo.libero
Synonyms: Cortisolo Libero
ru-RURussian (Russian Federation)
Кортизол.свободный
Synonyms: Cortisolo Libero
es-ESSpanish (Spain)
Cortisol libre
tr-TRTurkish (Turkey)
Kortizol.serb