LOINC
Version 2.70

LP32397-9IgG4Active

Description

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a “blocking” antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy [PMID: 26023323] . IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Copyright Copyright © 2006 Phadia AB. Source: Regenstrief LOINC, ImmunoCap

Basic Part Properties

Name
Ab.IgG4
Type
Suffix
Created On
2003-09-03
Construct for LOINC Short Name
IgG4

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP32397-9

Language Variants Get Info

zh-CNChinese (China)
抗体.IgG4
Synonyms: Ab.IgG4;IgG4;抗体 IgG4
nl-NLDutch (Netherlands)
As.IgG4
et-EEEstonian (Estonia)
antikehad.IgG4
fr-BEFrench (Belgium)
Anticorps. IgG4
fr-CAFrench (Canada)
, IgG4
it-ITItalian (Italy)
, Ab.IgG4
Synonyms: Anticorpi IgG4
ru-RURussian (Russian Federation)
Ат.IgG4
es-ESSpanish (Spain)
IgG4
tr-TRTurkish (Turkey)
Ab.IgG4
Synonyms: Ak.IgG4