LOINC
Version 2.73

LP34568-3NorbuprenorphineActive

Descriptions

LP34568-3   Norbuprenorphine
Buprenorphine (tradename Buprenex), is a long-lasting, high affinity opioid that acts on the same receptors as heroin and morphine but does not produce the same intense high or dangerous side effects. It is used for the treatment of pain and opioid dependence. The major buprenorphine metabolites are norbuprenorphine, buprenorphine-3-glucuronide (B3G), and norbuprenorphine-3-glucuronide (N3G). The analysis of buprenorphine and metabolites is performed to monitor compliance to drug therapy. Source: Regenstrief LOINC

LP34568-3   Norbuprenorphine
Norbuprenorphine is the primary active metabolite of buprenorphine, and its mean steady-state plasma concentration is comparable to or even exceeds that of buprenorphine following sublingual buprenorphine absorption (Kuhlman et al., 1998). It is likely to contribute to the overall pharmacological effects of buprenorphine. Buprenorphine and norbuprenorphine displayed distinct pharmacological properties at mu-opioid, delta-opioid, and kappa-opioid receptors and the ORL1 receptor. [PMID:11303059] Source: Regenstrief LOINC

Basic Part Properties

Name
Norbuprenorphine
Type
Component
Created On
2004-09-03
Construct for LOINC Short Name
Norbuprenorphine

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP34568-3

Language Variants Get Info

zh-CNChinese (China)
去甲基丁丙诺啡
Synonyms: 脱甲基丁丙诺啡;丁丙诺啡代谢产物;去甲丁丙诺啡;去甲基布诺啡;去甲布诺啡
nl-NLDutch (Netherlands)
norbuprenorfine
et-EEEstonian (Estonia)
Norbuprenorfiin
fr-BEFrench (Belgium)
Norbuprenorphine
fr-CAFrench (Canada)
Norbuprénorphine
it-ITItalian (Italy)
Norbuprenorfina
ru-RURussian (Russian Federation)
Норбупренорфин
es-ESSpanish (Spain)
Norbuprenorfina
Synonyms: Metabolito de la buprenorfina;NBU;norBUP
tr-TRTurkish (Turkey)
Norbuprenorfin
Synonyms: NBU