LP34568-3NorbuprenorphineActive
Descriptions
LP34568-3 Norbuprenorphine
Buprenorphine (tradename Buprenex), is a long-lasting, high affinity opioid that acts on the same receptors as heroin and morphine but does not produce the same intense high or dangerous side effects. It is used for the treatment of pain and opioid dependence. The major buprenorphine metabolites are norbuprenorphine, buprenorphine-3-glucuronide (B3G), and norbuprenorphine-3-glucuronide (N3G). The analysis of buprenorphine and metabolites is performed to monitor compliance to drug therapy.
Source: Regenstrief LOINC
LP34568-3 Norbuprenorphine
Norbuprenorphine is the primary active metabolite of buprenorphine, and its mean steady-state plasma concentration is comparable to or even exceeds that of buprenorphine following sublingual buprenorphine absorption (Kuhlman et al., 1998). It is likely to contribute to the overall pharmacological effects of buprenorphine. Buprenorphine and norbuprenorphine displayed distinct pharmacological properties at mu-opioid, delta-opioid, and kappa-opioid receptors and the ORL1 receptor. [PMID:11303059]
Source: Regenstrief LOINC
Basic Part Properties
- Name
- Norbuprenorphine
- Type
- Component
- Created On
- 2004-09-03
- Construct for LOINC Short Name
- Norbuprenorphine
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP34568-3
Language Variants Get Info
- zh-CNChinese (China)
- 去甲基丁丙诺啡
Synonyms: 脱甲基丁丙诺啡;丁丙诺啡代谢产物; 去甲丁丙诺啡; 去甲基布诺啡; 去甲布诺啡 - nl-NLDutch (Netherlands)
- norbuprenorfine
- et-EEEstonian (Estonia)
- Norbuprenorfiin
- fr-BEFrench (Belgium)
- Norbuprenorphine
- fr-CAFrench (Canada)
- Norbuprénorphine
- it-ITItalian (Italy)
- Norbuprenorfina
- ru-RURussian (Russian Federation)
- Норбупренорфин
- es-ESSpanish (Spain)
- Norbuprenorfina
Synonyms: Metabolito de la buprenorfina;NBU; norBUP - tr-TRTurkish (Turkey)
- Norbuprenorfin
Synonyms: NBU
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright