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LP34979-2Zinc finger protein of the cerebellum 4Active


LP34979-2   Zinc finger protein of the cerebellum 4
Paraneoplastic neurological syndrome (PNS) is an autoimmune disorder that is manifested by progressive central, peripheral and/or autonomic nervous system symptoms. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The antibodies that attack the neural tissue develop in response to tumor cells. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed.[PMID:22412264] Of patients positive for the zinc finger protein of the cerebellum 4 (Zic4) antibodies, ninety-two percent were diagnosed with small cell lung cancer. Zic4 antibodies often occur concurrently with Hu and CRMP5 antibodies.[PMID: 15007130 Source: Regenstrief LOINC

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Zinc finger protein of the cerebellum 4
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zh-CNChinese (China)
小脑锌指蛋白 4
Synonyms: Zic4;小脑锌指蛋白 4;Zinc finger protein of the cerebellum 4
nl-NLDutch (Netherlands)
zinc finger proteïne of the cerebellum 4
fr-BEFrench (Belgium)
Protéine-zinc en doigt du cervelet 4
fr-CAFrench (Canada)
Protéine à doigt de zinc du cervelet 4
it-ITItalian (Italy)
Zinc finger, proteina del cervelletto 4
Synonyms: Proteina zinc finger del cervelletto 4
ru-RURussian (Russian Federation)
Цинк-пальцевый белок мозжечка 4
es-ESSpanish (Spain)
Proteína dedo de zinc del cerebelo 4
Synonyms: Zic4
tr-TRTurkish (Turkey)
Çinko parmak proteini, serebellum 4'ün