Version 2.77


The 14-3-3 protein is a highly conserved family of proteins that was originally found in brain tissue in 1968. There are seven isoforms of 14-3-3 protein in mammals which are found in all eukaryotic cells. The proteins weigh between 25 and 30 kilo Daltons and interact with more than 200 target proteins. 14-3-3 proteins are able to easily move between the cytoplasm and the nucleus but are mainly found in the cytoplasm. 14-3-3 is an important regulator of cellular function including controlling the cycle of the cell, cell growth, differentiation, survival, apoptosis, migration and spreading. The isoform 14-3-3o is believed to have a role in human cancer development. PMID: 15857577 Source: Regenstrief LOINC

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Tag Language Translation
zh-CN Chinese (China) 14-3-3
fr-CA French (Canada) 14-3-3
et-EE Estonian (Estonia) 14-3-3
es-ES Spanish (Spain) 14-3-3
it-IT Italian (Italy) 14-3-3
tr-TR Turkish (Turkey) 14-3-3
ru-RU Russian (Russian Federation) 14-3-3
nl-NL Dutch (Netherlands) 14-3-3
fr-BE French (Belgium) 14-3-3