LOINC
Version 2.73

LP37577-1Centromere AbActive

Description

LP37577-1   Centromere Ab
Anti-centromere antibodies (ACA) occur in auto immune disorders; frequently in limited systemic scleroderma, (formerly called CREST Syndrome), and, occasionally are found in the diffuse form of scleroderma. They are rare in other rheumatic conditions and in healthy persons.

Anti-centromere antibodies are found in approximately 60% of patients with limited systemic scleroderma, and in 15% of those with diffuse form of scleroderma. The specificity of this test is >98%. Thus, a positive anticentromere antibody finding is strongly suggestive of limited systemic scleroderma. Anti-centromere antibodies present early in the course of disease, and is notably predictive of limited cutaneous involvement and a decreased likelihood of aggressive internal organ involvement, such as lung fibrosis.

When present in primary biliary cirrhosis, ACA are prognostic of portal hypertension. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Name
Centromere Ab
Type
Component
Created On
2006-05-09

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP37577-1

Language Variants Get Info

zh-CNChinese (China)
着丝点抗体
Synonyms: 着丝点 Ab;着丝粒 Ab;着丝粒抗体