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LP417746-7Alpha defensins 1+2+3Active


LP417746-7   Alpha defensins 1+2+3
Human neutrophil peptides (HNPs), also known as alpha defensins, are antimicrobial peptides released by activated neutrophils in response to infection. HNP-1 and HNP-2 are encoded by the DEFA1 gene, and HNP-3 is encoded by DEFA3 gene. All three peptides are nearly identical; they only differ by the first amino acid in their sequence. HNPs have antibacterial, fungicide and antiviral activities.[PMID:15616305] They have been extensively studied as a biomarker in various diseases such as infections, atherosclerosis, rheumatic diseases, preeclampsia, and cancer.[PMID:16513165][PMID:19186224][PMID:25196784] HNP synovial fluid proteins are used as a diagnostic biomarker for periprosthetic joint infection (PJI).[PMID:31856885] Source: Regenstrief LOINC

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Alpha defensins 1+2+3
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Alpha defensins 1+2+3

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zh-CNChinese (China)
Alpha 防御素 1+2+3
Synonyms: α防御素 1+2+3;Alpha 防卫素 1+2+3;α防卫素 1+2+3
nl-NLDutch (Netherlands)
alfa-defensine 1 + 2 + 3
it-ITItalian (Italy)
Alfa defensine 1+2+3
es-ESSpanish (Spain)
Alfa defensinas 1+2+3