LOINC
Version 2.72

LP417746-7Alpha defensins 1+2+3Active

Description

LP417746-7   Alpha defensins 1+2+3
Human neutrophil peptides (HNPs), also known as alpha defensins, are antimicrobial peptides released by activated neutrophils in response to infection. HNP-1 and HNP-2 are encoded by the DEFA1 gene, and HNP-3 is encoded by DEFA3 gene. All three peptides are nearly identical; they only differ by the first amino acid in their sequence. HNPs have antibacterial, fungicide and antiviral activities.[PMID:15616305] They have been extensively studied as a biomarker in various diseases such as infections, atherosclerosis, rheumatic diseases, preeclampsia, and cancer.[PMID:16513165][PMID:19186224][PMID:25196784] HNP synovial fluid proteins are used as a diagnostic biomarker for periprosthetic joint infection (PJI).[PMID:31856885] Source: Regenstrief LOINC

Basic Part Properties

Name
Alpha defensins 1+2+3
Type
Component
Created On
2020-02-18
Construct for LOINC Short Name
Alpha defensins 1+2+3

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP417746-7

Language Variants Get Info

zh-CNChinese (China)
Alpha 防御素 1+2+3
Synonyms: α防御素 1+2+3;Alpha 防卫素 1+2+3;α防卫素 1+2+3
nl-NLDutch (Netherlands)
alfa-defensine 1 + 2 + 3
it-ITItalian (Italy)
Alfa defensine 1+2+3
es-ESSpanish (Spain)
Alfa defensinas 1+2+3