Version 2.79

Description

Bacillus anthracis lethal factor is one of the three components of the anthrax toxin produced by the bacterium Bacillus anthracis, which causes anthrax. This protein acts as a zinc-dependent metalloprotease that, when combined with protective antigen (PA) and entering host cells, disrupts cellular signaling by inactivating mitogen-activated protein kinases (MAPKs), leading to cell death, particularly in immune cells like macrophages, and contributing to the overall pathogenic effects of anthrax infection. Source: LOINC

Basic Part Properties

Part Name
Bacillus anthracis lethal factor
Part Display Name
Bacillus anthracis lethal factor
Part Type
Component (Describes the core component or analyte measured)
Created On
2024-11-12
Construct for LOINC Short Name
B. anthracis LF

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP444041-0