LOINC
Version 2.73

LP70657-9RPRActive

Description

LP70657-9   RPR
The Rapid Plasma Reagin test (RPR) is a macroscopic flocculation test that uses cardiolipin-lecithin-cholesterol antigen coupled to carbon particles. The test detects non-specific antibodies directed against substances released by cells infected with Treponema pallidum, the organism that causes syphilis. The term "reagin" means that this test does not look specifically for antibodies against T. pallidum.
In addition to screening for syphilis, an RPR level (also called a "titer") can be used to track the progress of the disease over time and its response to therapy.
The RPR test is effective at screening patients who have syphillis but not the symptoms but in contrast, it may indicate that people have syphilis who in reality do not ( false positives). False positives can be seen in viral infections such as (Epstein-Barr, hepatitis, varicella, measles), lymphoma, tuberculosis, malaria, endocarditis, connective tissue disease, pregnancy, autoimmune diseases, intravenous drug abuse, or contamination. It can also be positive in uninfected elderly. As a result, an RPR test should always be followed up by a more specific treponemal test. Treponema pallidum hemagglutination assay (TPHA) and Fluorescent Treponemal Antibody Absorption (FTA-ABS) tests are more specific but are more expensive. Unfortunately, even with TPHA and FTA-ABS false positives can still occur in related treponomal infections such as yaws and pinta. Source: Regenstrief LOINC

Basic Part Properties

Name
RPR
Type
Method
Created On
2008-08-21
Construct for LOINC Short Name
RPR

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP70657-9

Language Variants Get Info

zh-CNChinese (China)
RPR
Synonyms: Rapid Plasma Reagin;快速血浆反应素;快速血浆反应素(环状卡片试验);rapid plasma reagin card test for syphilis;快速梅毒血浆反应素卡片试验
nl-NLDutch (Netherlands)
PRP
Synonyms: rapid plasma reagin
et-EEEstonian (Estonia)
RPR
fr-BEFrench (Belgium)
RPR
el-GRGreek (Greece)
RPR
it-ITItalian (Italy)
RPR
pl-PLPolish (Poland)
Test kiłowy, reaginowy RPR
Synonyms: szybki test na obecność antygenu w osoczu (RPR)
ru-RURussian (Russian Federation)
Антикардиолипиновый тест
Synonyms: Rapid Plasma Reagin
es-ESSpanish (Spain)
RPR
tr-TRTurkish (Turkey)
RPR