LP71695-8
Mutated citrullinated vimentin Ab
Active
Description
Detection of autoantibodies against mutated citrullinated vimentin is part of RA diagnostics (rheumatoid arthritis), especially in sera negative for rheumatoid factor (RF negative sera). Anti-MCV antibodies are member of ACPA family, a group of the so called antibodies to citrullinated protein/peptide antigens.
In rheumatology diagnostics, autoantibodies against mutated citrullinated vimentin (anti-MCV) are of prominent diagnostic and prognostic value. Their significance is greater than that of rheumatoid factor.
Anti-MCV are used as efficient biomarkers for estimating progress of rheumatoid arthritis. Main advantage of testing for anti-MCV is the early appearance of the anti-MCV antibodies, what allows for detection of early RA and submits adequate therapy just after the disease's onset. Moreover, anti-MCV titres show strong correlation to disease activity, disease severity and the success of therapy.
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Source: Wikipedia
, Wikipedia
Basic Part Properties
- Part Name
- Mutated citrullinated vimentin Ab
- Part Display Name
- Mutated citrullinated vimentin Ab
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2008-10-30
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