FLT3-ITD test mapping

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    Jo Shum Ka Yan
    Participant

    Hello,

    We would like to get input from the LOINC community regarding the FLT3-ITD test mapping granularity.

    We have a local test reporting FLT3-ITD mutation detected and another local test reporting the FLT3-ITD mutation detected in exon 14 and 15 (1). We know that FLT3-ITD mutation can be detected in exon 11& 12 (2) from publications. Should we create 2 local LOINC codes* for exon specific and non-specific tests?

    * LOINC has no office code for FLT3-ITD test at this moment yet.

    Regards,

    Jo SHUM

     

     

    (1) Detection of FLT3 Oncogene Mutations in Acute Myeloid Leukemia Using Conformation Sensitive Gel Electrophoresis

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635624/

    (2) Detection of FLT3 Internal Tandem Duplication and D835 Mutations by a Multiplex Polymerase Chain Reaction and Capillary Electrophoresis Assay

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1907323/

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