Jamalynne Deckard

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Viewing 15 posts - 1 through 15 (of 19 total)
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  • Tony,

    Thank you for notifying us of the inconsistency in the Long Common Name for the microalbumin terms. I fixed the issue, and the correction will appear in the next release (February). Those with a detection limit of <=3.0 mg/L will state “Microalbumin” in the Long Common Names.

    Thank you,

    Jami Deckard

    LOINC Terminology Developer


    Thank you for your interest in processing LOINC codes for various psychiatric scales and score terms! Please note that in general, we request that you submit separate submissions for each instrument, and we will need to sort out copyright prior to processing any request. The submitter is actively involved in seeking & obtaining copyright approval, which is needed prior to including in LOINC (if the instrument is copyrighted). Additionally, we advise requesting no more than 50 terms at a time unless we are doing the work as part of a contract. Feel free to contact us through our online form (https://loinc.org/contact/), and we can set up a call to discuss further.

    Thank you!

    Hello Pam & Brittany!

    The Sequencing Method in LOINC includes methods like Sanger & NGS that are used to detect variants within the coding regions and typically intron/exon boundaries of a gene (i.e. full gene analysis).

    Here’s the current description for Sequencing in LOINC:

    Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. [PMID: 271968] Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This “high-throughput” technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. [PMID: 18576944] Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. [PMID: 20858600]

    As Pam mentioned above, the Method of Molgen is used when a variety of methods could be used as part of the analysis.  This is common for chromosome studies, targeted variant analysis, and large deletion/duplication analysis.



    LOINC Content Developer


    in reply to: LOINC PrThr values with MCnc example units? #428919


    Thank you for your post. You are correct that these should not have example units. I reviewed the terms with PrThr as the Property and having example UCUM units.  The issue occurred with our internal processing and will be fixed in the next release (December).  The expected results for PrThr would be ordinal, e.g. Present/Absent, Detected/Not detected, 1+/2+/3+, etc. Such results are based on either a cut-off (threshold) value or the presence of the analyte — hence the Property of “PrThr” or “Presence or Threshold”.



    in reply to: Liddle Syndrome #21012

    Hi Panu,

    Genetic tests in LOINC are typically named based on the genes tested. The disease names should be included as synonyms (related names) so users can find the tests when searching in LOINC. For Liddle Syndrome, these genes are likely SCNN1B and SCNN1G, which we currently do not have codes for in LOINC. We welcome a request for new terms. For information on how to submit a request, please visit https://loinc.org/submissions/.

    Thank you,

    in reply to: Morbitity and Mortality Summary Stats #20560

    Hi Mike,

    You may have already found these terms. If not, here they are:

    82844-2 Number affected by condition Population

    82843-4 Number dead from condition Population

    LOINC Content Developer

    in reply to: System type for Micro Antibody tests #17910


    Yes, we welcome a formal request for updating Systems from Ser or Plas to Ser/Plas. Updates to LOINC terms can be made through the loinc.org website at https://loinc.org/submissions/revisions/. Please provide documentation to support the update request.

    FYI from Page 28 of the LOINC Users’ Guide:

    For many types of tests, the distinction between plasma and serum is irrelevant. When testing on serum or
    plasma is clinically equivalent, the System should be recorded as Ser/Plas, meaning “either Serum or Plasma”.
    Note that the use of a LOINC code with Ser/Plas as the System to report the result of a specific manufacturer’s
    assay does not imply that the given assay is approved for use with both serum and plasma specimens; it simply
    means that the results obtained from testing serum and plasma are clinically equivalent, independent of which
    assay was used. Sometimes the test can only be run on either plasma or serum; the Component will then be
    associated with either Ser or Plas in one observation. If the test can be run on either but the results are clinically different and standardized (a very rare circumstance), two separate tests will be defined in our file, one with a
    System Plas and one with a System Ser. The current LOINC database includes some Ser tests and some Plas tests that should really be Ser/Plas. As we determine that a Ser or Plas test really should have been designated Ser/
    Plas, we will change the designation.

    Thank you!
    Jami Deckard
    LOINC Content Developer

    in reply to: HCG.beta unit with WHO 5th IS #17303

    Wai Kin Cheung,

    Thank you for your post.

    We suggest the use of test codes without IS in their name and encourage labs to report that information either as text in the method field of the HL7 message or in a comment when they think it is important.

    We have found that laboratories are often inconsistent about the use of the various IS standard in their test names. Additionally, one reason for changing of IS standards is that the control specimens for the existing standard run out. This does not always mean a real difference in the new IS standard compared to the old. Further, the tests for pituitary hormones vary greatly in their test results because of the differences in the fragment and sections of the polypeptides they pick up. So on the one hand, it has been difficult to know what IS standard a given lab is really using when they make a submission to LOINC. On the other hand, differences in test methods create intrinsic noise in these tests.

    So with advice from our laboratory chemistry experts, Regenstrief has decided not to try and keep up with the IS distinctions and should probably discourage the use of the terms with IS in their name.

    We welcome input on these decisions.


    Jami Deckard, MS
    LOINC Content Developer
    Regenstrief Institute, Inc.

    in reply to: 75219-6 Summary registry report #17264

    A summary registry report could represent a collection of patient data included in a registry or reported to an organization who manages a registry (or database) for a given cause or reason.  The data may then be analyzed by the organization and reported to interested parties (government, etc.) who would use the results to develop programs, for example, to improve patient care based on the data.

    In addition to the general code – 75219-6, we currently have three codes for more focused/defined registries:

    75609-8            Birth defects registry report       Find      Pt         Outpatient         Doc      {Author Type}

    74264-3            Summary registry report            Find      Pt         {Setting}           Doc      HIV

    74198-3            Summary registry report            Find      Pt         {Setting}           Doc      Trauma



    in reply to: What is Coronary Calcium actually? #16680

    You can find information about coronary calcium here: http://www.nhlbi.nih.gov/health/health-topics/topics/cscan/

    I agree that it doesn’t appear LOINC has an existing code for reporting the calcium (or Agatston) score. You can send a formal submission to submissions@loinc.org. See http://loinc.org/submissions for more information.


    Hi Barry,

    We have a few codes for HBA1 and HBA2 gene mutation analysis that may work. They can be viewed here: http://search.loinc.org/search.zul?query=hba1+or+hba2+or+hbz*. If the lab is testing for a specific mutation or deletion, we recommend mapping to the corresponding LOINC code (e.g, LOINC 55247-1).

    Currently we do not have codes for HBZ gene testing. We welcome a formal submission sent to submissions@loinc.org. For more information, see http://loinc.org/submissions.

    The current model for how LOINC names molecular genetic tests is described in the User’s guide, Section 3.9: http://loinc.org/downloads/files/LOINCManual.pdf

    Hope this helps!

    Jami Deckard, MS
    LOINC Content Developer

    in reply to: Licensing of instruments #16665

    Additional permission is not needed if the external copyright notice (when provided with a term) is included in the publication.

    Section 9 of the LOINC Copyright Notice and License (see http://loinc.org/terms-of-use) discusses the terms to which users may incorporate LOINC content into an implementation guide or other technical specification.

    Specifically, Section 9e states users are required to either:
    i) Include the EXTERNAL_COPYRIGHT_NOTICE, or
    ii) Exclude information from the rows that include third party copyrighted content (e.g., third party survey instruments and answers). If third party content is included, users are required to comply with any such third party copyright license terms.

    Jami Deckard, MS
    LOINC Content Developer
    Regenstrief Institute, Inc.

    in reply to: Codes vs scores for scales #16668

    We agree, typing the values as integers seems appropriate.

    Jami Deckard, MS
    LOINC Content Developer
    Regenstrief Institute, Inc.

    in reply to: CBC Panels #16640


    Thanks for your comments and suggestion about replacing “W” to “with” in the long common name of LOINC codes. The W does stand for with, but this may not always be clear. We will pass your suggestion along to the LOINC team.

    in reply to: reporting CT values in molecular tests #16645

    I agree that the cycle or cross threshold (CT) value for real-time PCR is not an interpretation. I suggest requesting a quantitative code similar to the following since the result is numerical:

    Salmonella enterica DNA Threshold Pt XXX Qn Probe.amp.tar

Viewing 15 posts - 1 through 15 (of 19 total)