35142-9Amphiphysin Ab [Titer] in Cerebral spinal fluidActive
Part Descriptions
LP30843-4 Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein.
Source: Regenstrief LOINC
LP37039-2 Amphiphysin Ab
Paraneoplastic syndromes (PNS) are diseases associated with remote effects of tumors, of which small-cell lung cancer (SCLC), ovarian cancer, breast cancer, thymoma, Hodgkin lymphoma, and testicular cancer are the most common. Stiff-person syndrome (SPS) is a rare neurological disorder characterized by stiffness of skeletal muscles with superimposed spasms, which can have an idiopathic or paraneoplastic component. First described in women with breast cancer and SPS, amphiphysin antibodies have been reported in patients with diverse paraneoplastic neurological disorders, and cancers. Amphiphysin antibodies are considered diagnosic for paraneoplastic neurologic syndromes and can direct the search for an occult tumor, recurrence of tumor, or second tumor.
Source: ARUP Laboratories
LP37039-2 Amphiphysin Ab
Amphiphysin is a brain-enriched protein normally found only within the membrane of synaptic vesicles in neural tissue. Antibodies against amphiphysin (128kDa) are directed against the protein amphiphysin, and their presence plays an important diagnostic role in paraneoplastic syndromes (e.g. Lambert Eaton myasthenia syndrome, encephalomyelitis with rigidity, cerebellar syndrome, sensory neuronopathy, opsoclonus myoclonus ataxia, and Stiff-man syndrome). Paraneoplastic syndromes are autoantibody-mediated neurologic disorders most commonly associated with cancers of the lung, breast, ovaries or lymphatic system.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Amphiphysin Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- Qn
- Method
Additional Names
- Short Name
- Amphiphysin Ab Titr CSF
- Display Name
- Amphiphysin Ab (CSF) [Titer]
- Consumer Name Alpha
- Amphiphysin antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.11
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common US Lab Results Rank
- 4882
Member of these Groups
LG14304-6 | Amphiphysin Ab| |
Language Variants Get Info
- zh-CNChinese (China)
- 双载蛋白 抗体:
滴定度: 时间点: 脑脊液: 定量型: - nl-NLDutch (Netherlands)
- amfifysine As:
titer: moment: liquor cerebrospinalis: kwantitatief: - et-EEEstonian (Estonia)
- Amfifüsiin antikehad:
Titr: Pt: CSF: Qn: - fr-BEFrench (Belgium)
- Amphiphysine Ac:
Titre: Temps ponctuel: LCR: Quantitatif: - fr-CAFrench (Canada)
- Amphiphysine , Ac:
Titre: Temps ponctuel: LCR: Quantitatif: - fr-FRFrench (France)
- Amphiphysine anticorps:
Titre: Ponctuel: Liquide céphalorachidien: Numérique: - it-ITItalian (Italy)
- Amfifisina Ab:
Titr: Pt: LCS: Qn: - ko-KRKorean (Korea, Republic of)
- Amphiphysin Antibody:
역가: 검사시점: 뇌척수액: 정량: - pt-BRPortuguese (Brazil)
- Amfifisina Ac:
Título: Pt: LCR: Qn: - ru-RURussian (Russian Federation)
- Амфифизин Ат:
Титр: ТчкВрм: ЦСЖ: Колич: - es-ARSpanish (Argentina)
- anticuerpo conra anfifisina:
factor de dilución (titulación): punto en el tiempo: líquido cefalorraquídeo: cuantitativo: - es-MXSpanish (Mexico)
- Amphiphysin Ab:
Título: Punto temporal: Fluído espinal cerebral: Cuantitativo: - es-ESSpanish (Spain)
- Anfifisina Anticuerpos:
Titulo / Factor de dilución: Punto temporal: Líquido Cefalorraquideo: Qn: - tr-TRTurkish (Turkey)
- Amfifizin Ab:
Titr: Zmlı: BOS: Kant:
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
titer | REGENSTRIEF |
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=35142-9
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright