LOINC
Version 2.73

47255-5Procollagen type I.N-terminal propeptide [Mass/volume] in SerumActive

Part Descriptions

LP57671-7   Procollagen type I.N-terminal propeptide
Procollagen type I N-terminal propeptide is considered a sensitive marker of bone formation and it is particularly useful for monitoring treatment for osteoporosis in postmenopausal women, and Paget's disease of the bone. Type I collagen constitutes 90% of bone proteins and is synthesized as type I procollagen. During the extracellular processing of type I procollagen, the amino terminal [N-terminal propeptide of type I collagen] and carboxy terminal propeptide are separated. These propeptides circulate in the bloodstream, where they are markers of bone formation. Procollagen type I N-terminal propeptide circulates as different forms, including the intact authentic trimeric procollagen type I N-terminal propeptide, a monomer, and several fragments.[PMID:17998267] Source: Regenstrief LOINC, PMID: 17998267

LP57671-7   Procollagen type I.N-terminal propeptide
A procollagen peptide contains an additional peptide sequence, termed the propeptide, at its amino and carboxy terminal ends. Collagen types I, II, III, IV and V are synthesized as precursor molecules called procollagens. Propeptides facilitate the winding of procollagen molecules into a triple-helix conformation within the endoplasmic reticulum. These propeptides are then cleaved from the collagen triple helix molecule during its secretion, after which the collagens polymerize into extracellular collagen fibrils. Thus, the amount of free propeptides directly correlates with collagen molecule synthesis. Procollagen Type I C-peptide (PIP) has also been extensively referenced in correlation studies between collagen levels and certain health disorders such as bone disease, alcoholic liver disease, liver cirrhosis and cirrhosis (Borrmann type IV) adenocarcinoma of the stomach. Source: Regenstrief Help

Fully-Specified Name

Component
Procollagen type I.N-terminal propeptide
Property
MCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
PINP Ser-mCnc
Display Name
Procollagen type I.N-terminal propeptide (S) [Mass/Vol]
Consumer Name Alpha
Procollagen Type I.N-terminal Propeptide, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73
Order vs. Observation
Both
Common US Lab Results Rank
4299

Member of these Groups

LG18642-5 Procollagen type I.N-terminal propeptide|MCnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
前胶原肽.I 型 N-末端:质量浓度:时间点:血清:定量型:
nl-NLDutch (Netherlands)
procollageenpeptide.type 1 N-terminaal:massa/volume:moment:serum:kwantitatief:
et-EEEstonian (Estonia)
I tüüpi prokollageeni N-fragment:MCnc:Pt:S:Qn:
fr-BEFrench (Belgium)
Peptide du procollagène.type 1 N-terminal:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-CAFrench (Canada)
Procollagène type I.N-terminal propeptide:Concentration de masse:Temps ponctuel:Sérum:Quantitatif:
fr-FRFrench (France)
Procollagène type 1 propeptide N terminal:Masse/Volume:Ponctuel:Sérum:Numérique:
de-DEGerman (Germany)
Prokollagenpeptid Typ 1.Propeptid N-Terminal:Massenkonzentration:Zeitpunkt:Serum:Quantitativ:
it-ITItalian (Italy)
Procollagene, peptide.tipo 1 N-Terminale:MCnc:Pt:Siero:Qn:
pt-BRPortuguese (Brazil)
Peptídeo procolágeno.Tipo 1 N-Terminal:MCnc:Pt:Soro:Qn:
ru-RURussian (Russian Federation)
Проколлаген пептид.тип 1 N-Терминаль:МассКонц:ТчкВрм:Сыв:Колич:
es-MXSpanish (Mexico)
Propéptido N-terminal de procolágeno tipo I.:Concentración de masa:Punto temporal:Suero:Cuantitativo:
es-ESSpanish (Spain)
Péptido N-terminal del procolágeno tipo I:Concentración de masa:Punto temporal:Suero:Qn:
tr-TRTurkish (Turkey)
Prokollajen peptid.tip 1 N-Terminal:KütlKons:Zmlı:Ser:Kant:

Example Units

Unit Source
ug/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47255-5