LOINC
Version 2.73

49308-0Neutrophil cytoplasmic Ab pattern [Interpretation] in Serum by Immunofluorescence NarrativeActive

Part Description

LP16728-5   Neutrophil cytoplasmic
Neutrophil cytoplasmic antibodies are autoantibodies that bind to the granulocytes of neutrophils. These antibodies were first identified in patients with Wegener's granulomatosis (WG) who also had systemic vasculitis and necrotizing crescentic glomerulonephritis. When viewed under a fluorescent microscope, a typical cytoplasmic fluorescent pattern is visible. These ANCA are called cytoplasmic ANCA (c-ANCA) and the antigen they target is proteinase 3 (PR3) which is part of the azurophilic granules of neutrophils. The perinuclear ANCA (p-ANCA) targets the antigen myeloperoxidase (MPO) and is associated with idiopathic forms of systemic vasculitis and glomerulonephritis. A third ANCA antibody is the atypical ANCA (a-ANCA). The presence of a-ANCA has been found in patients with inflammatory bowel diseases including ulcerative colitis (UC) and Crohn's disease (CD), autoimmune-mediated liver diseases, rheumatoid arthritis RA, and systemic lupus erythematosus (SLE).[PMID:27366026] Source: Regenstrief LOINC

Fully-Specified Name

Component
Neutrophil cytoplasmic Ab pattern
Property
Imp
Time
Pt
System
Ser
Scale
Nar
Method
IF

Additional Names

Short Name
ANCA Ab pattern Ser IF-Imp
Display Name
Neutrophil cytoplasmic Ab pattern IF Nar (S) [Interp]
Consumer Name Alpha
Interpretation of Neutrophil cytoplasmic Ab pattern test result, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.73
Order vs. Observation
Observation
Common US Lab Results Rank
18909

Member of these Groups

LG7000-5 Neutrophil cytoplasmic Ab pattern|Imp|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
嗜中性粒细胞细胞浆 抗体模式:印象:时间点:血清:叙述型:免疫荧光法
nl-NLDutch (Netherlands)
neutrofiel cytoplasmatisch As-patroon:interpretatie:moment:serum:tekstueel:immunofluorescentie
fr-BEFrench (Belgium)
Neutrophile cytoplasmique Anticorps.Profil des Ac:Impression/interprétation d'étude:Temps ponctuel:Sérum:Narratif:Immunofluorescence
fr-CAFrench (Canada)
Neutrophile cytoplasmique , Patron des Ac:Impression/interprétation d'étude:Temps ponctuel:Sérum:Narratif:Immunofluorescence
fr-FRFrench (France)
Cytoplasme des polynucléaires neutrophiles anticorps aspect:Interprétation:Ponctuel:Sérum:Résultat textuel:Immunofluorescence
de-DEGerman (Germany)
Neutrophiler zytoplasmatischer Ak-Muster:Interpretation:Zeitpunkt:Serum:Freitext:Immunfluoreszenztest
it-ITItalian (Italy)
Neutrofilo citoplasmico profilo Ab:Imp:Pt:Siero:Nar:IF
pt-BRPortuguese (Brazil)
Citoplasma dos Neutrófilos Ac padrão:Imp:Pt:Soro:Nar:Imunofluorescência
ru-RURussian (Russian Federation)
Нейтрофилов цитоплазматический Ат паттерн:Впчт:ТчкВрм:Сыв:Опис:ИФ
es-MXSpanish (Mexico)
Patrón de Ab citoplasmático de neutrófilos:Impresión / interpretación del estudio:Punto temporal:Suero:Narrativo:Inmunofluorescencia (IF)
es-ESSpanish (Spain)
Citoplasma de neutrófilo Patrón de anticuerpos:Impresión/interpretación del estudio:Punto temporal:Suero:Narrativo:Inmunofluorescencia (IF)
tr-TRTurkish (Turkey)
Nötrofil sitoplazmik Ab yapısı:İzlnm:Zmlı:Ser:Öykü:IF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49308-0