Version 2.73

53020-4Complement C1q Ab [Presence] in SerumActive

Part Descriptions

LP16352-4   Complement C1q
A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY. Source: National Library of Medicine, MeSH 2006

LP16352-4   Complement C1q
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement (C1) is composed of 3 subunits: C1q, C1r, and C1s. Complement C1q initiates the complement pathway by binding to immunoglobulins. Absent or decreased levels of Complement C1q are seen in patients with acquired angioedema, systemic lupus erythematosus (SLE), polymyositis, and other immune complex diseases. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency. Source: Regenstrief Institute

Fully-Specified Name

Complement C1q Ab

Additional Names

Short Name
C1q Ab Ser Ql
Display Name
Complement C1q Ab Ql (S)
Consumer Name Alpha
Complement C1q antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.24
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
补体 C1q 抗体:存在情况或阈值:时间点:血清:序数型:
nl-NLDutch (Netherlands)
complement C1q As:aanwezigheid:moment:serum:ordinaal:
et-EEEstonian (Estonia)
Komplemendi komponent C1q antikehad:PrThr:Pt:S:Ord:
fr-BEFrench (Belgium)
Complément C1q Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
fr-CAFrench (Canada)
Complément C1q , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FRFrench (France)
Complément C1q anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
de-DEGerman (Germany)
Komplement C1q Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:
it-ITItalian (Italy)
Complemento C1q Ab:PrThr:Pt:Siero:Ord:
pt-BRPortuguese (Brazil)
Complemento C1q Ac:ACnc:Pt:Soro:Ord:
ru-RURussian (Russian Federation)
Комплемент C1q Ат:PrThr:ТчкВрм:Сыв:Пор:
es-MXSpanish (Mexico)
Complemento C1q Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:
es-ESSpanish (Spain)
Complemento C1q Anticuerpos:PrThr:Punto temporal:Suero:Ord:
tr-TRTurkish (Turkey)
Kompleman C1q Ab:MevcEşik:Zmlı:Ser:Srl:

LOINC FHIR® API Example - CodeSystem Request Get Info