LOINC
Version 2.73

63440-2PCA-Tr Ab [Presence] in Serum by ImmunoblotActive

Part Description

LP31709-6   Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE).[PMID:22412264] PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed.[PMID:22412264] Source: Regenstrief LOINC, Cytoplasmic

Fully-Specified Name

Component
Purkinje cell cytoplasmic type Tr Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IB

Additional Names

Short Name
PCA-Tr Ab Ser Ql IB
Display Name
PCA-Tr Ab IB Ql (S)
Consumer Name Alpha
PCA-Tr antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Changed "Purkinje cells" in Component to the more common name, "Purkinje cell cytoplasmic".
Order vs. Observation
Both
Common US Lab Results Rank
8194

Member of these Groups

LG29451-8 Purkinje cell cytoplasmic type Tr Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
浦肯雅细胞胞浆 Tr 型 抗体:存在情况或阈值:时间点:血清:序数型:免疫印迹法
nl-NLDutch (Netherlands)
purkinjecellen type Tr As:aanwezigheid:moment:serum:ordinaal:immunoblotting
fr-BEFrench (Belgium)
Cellules de Purkinje type TR Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-CAFrench (Canada)
Cellules de Purkinje cytoplasmique type Tr , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-FRFrench (France)
Tr anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
it-ITItalian (Italy)
Cellule di Purkinje tipo Tr Ab:PrThr:Pt:Siero:Ord:IB
ru-RURussian (Russian Federation)
Пуркинье клетки тип Tr Ат:PrThr:ТчкВрм:Сыв:Пор:ИБ
es-MXSpanish (Mexico)
Citoplasma de células de Purkinje tipo Tr Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunotransferencia
es-ESSpanish (Spain)
Células de Purkinje tipo Tr Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
tr-TRTurkish (Turkey)
Purkinje hücreleri tip Tr Ab:MevcEşik:Zmlı:Ser:Srl:IB

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63440-2