Version 2.73

85840-7Beta-lactam resistance ESBL blaVEB gene [Presence] by Molecular methodActive

Term Description

This test reports the presence of the blaVEB extended spectrum beta lactamase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC

Part Description

LP248286-9   Bacterial beta-lactam resistance ESBL blaVEB gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some gram negative bacilli that confer resistance to the majority of beta-lactam antibiotics, include the penicillins, cephalosporins and the monobactam aztreonam. ESBLs are most often plasmid-borne. Specific ESBLs include TEM, SHV, and the CTX-M groups, which are the most clinically prevalent, and VEB, PER, BEL, and GES, which are less common. [PMID:19246801] -TEM and SHV subtypes are derived from amino acid substitutions, resulting in enzymatic hydrolysis of many beta-lactam antibiotics. -CTX-M genes originate from Kluyvera species. They are separated based on their amino acid sequences into the following groups: CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-8, and CTX-M-25. -VEB, PER, BEL, and GES genes are less common. [Mayo Medical Laboratories] The nomenclature for ESBL genes includes the prefix "bla", which stands for "beta-lactam", followed by the enzyme (ie. blaTEM). Source: Regenstrief LOINC

Fully-Specified Name

Bacterial beta-lactam resistance ESBL blaVEB gene

Additional Names

Short Name
ESBL blaVEB gene Islt/Spm Ql
Display Name
Beta-lactam resistance ESBL blaVEB gene Molgen Ql (Islt/Spec)
Consumer Name Alpha
Beta-lactam Resistance ESBL blaVEB gene

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.61
Last Updated
Version 2.67
Change Reason
Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation

Member of these Panels

LOINC Long Common Name
93698-9 Gram negative bacterial resistance panel by Molecular genetics method

Language Variants Get Info

zh-CNChinese (China)
细菌 beta-内酰胺耐药 ESBL blaVEB 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
nl-NLDutch (Netherlands)
bacteriële bètalactamresistentie ESBL blaVEB-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
fr-FRFrench (France)
Résistance bactérienne aux bêta lactamases ESBL blaVEB gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
de-DEGerman (Germany)
Bakterielle Beta-Lactam-Resistenz ESBL blaVEB-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
it-ITItalian (Italy)
Resistenza batterica beta-lactamica, gene ESBL blaVEB:PrThr:Pt:Isolato/Campione:Ord:Molgen
es-MXSpanish (Mexico)
Resistencia bacteriana a betalactámicos BLEE gen blaVEB:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
es-ESSpanish (Spain)
gen bacteriano ESBL blaVEB resistente a beta-lactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular

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