LP157222-3Centromere protein AActive

Description

LP157222-3   Centromere protein A
Centromere protein A (CENP-A) is an essential centromere protein encoded by the CENPA gene. Overexpression of CENP-A causes chromosomal aberrations, and depletion of CENP-A promotes apoptosis and induces cell cycle arrest. Overexpression of CENP-A has been associated with high grade cancers and is a prognostic factor for patients with estrogen receptor (ER)-positive breast cancer. Antibodies to CENP-A are associated with scleroderma, systemic sclerosis, CREST syndrome, and other rheumatologic diseases. Source: Regenstrief LOINC

Basic Part Properties

Name

Centromere protein A

Type

Component

Created On

2012-08-22

Construct for LOINC Short Name

CENP A

LOINC FHIR^® API Example - CodeSystem Request Get Info

Language Variants Get Info

zh-CNChinese (China)

着丝粒蛋白 A
Synonyms: 着丝点蛋白 A;centromere protein A;CENP-A;CENPA

nl-NLDutch (Netherlands)

centromeereiwit A

it-ITItalian (Italy)

Centromero, proteina A

ru-RURussian (Russian Federation)

Центромерный протеин A

es-ESSpanish (Spain)

Proteína A del centrómero (CENP-A)

tr-TRTurkish (Turkey)

Sentromer protein A

LOINC Copyright

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