LP220413-1TIF1-gammaActive

Description

LP220413-1   TIF1-gamma
Transcriptional intermediary factor 1-gamma (TIF1-gamma or E3 ubiquitin-protein ligase TRIM33), induces inactivation of the SMAD4 protein, which promotes cell growth (including malignant tumours) by inhibiting the anti-proliferative effects of TGF-beta. Anti-TIF1-gamma autoantibodies have been associated with adult- and juvenile-onset dermatomyositis (DM), and particularly with cancer-associated DM. [PMID:20501546] Source: Regenstrief LOINC, PMID: 20501546

Basic Part Properties

Name

TIF1-gamma

Type

Component

Created On

2016-07-07

Construct for LOINC Short Name

TIF1-gamma

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Language Variants Get Info

zh-CNChinese (China)

TIF1-gamma
Synonyms: TIF1-γ;TIF1-gamma;转录中介因子 1-γ;转录中介因子 1-gamma;Transcriptional intermediary factor 1-gamma;E3 泛素连接酶 TRIM33;E3 ubiquitin-protein ligase TRIM33

nl-NLDutch (Netherlands)

TIF1-gamma

it-ITItalian (Italy)

TIF1-gamma

es-ESSpanish (Spain)

TIF1-gamma

LOINC Copyright

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