Version 2.73

LP31258-4Clostridium botulinum toxin AActive


LP31258-4   Clostridium botulinum toxin A
Botulinum toxin is a neurotoxin produced by Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod found on plants, in soil, water and the intestinal tracts of animals. Eight exotoxins (A, B, C1, C2, D, E, F and G) have been identified, all of which interfere with neural transmission by blocking the release of acetylcholine, the principal neurotransmitter at the neuromuscular junction. The toxins are used in the clinical management of various spastic medical conditions, strabismus and focal dystonias, hemifacial spasms, headaches, hyper-salivation and hyperhidrosis. Type A is the most potent toxin. In 2002 it was approved by the U.S. Food and Drug Administration for cosmetological uses. It is administered by injection into muscles or glands with the effects lasting approximately three months. Most patients require multiple treatments over many years and some develop tolerance to the injections due to the development of neutralizing antibodies to the toxin. Side effects are minor and transient. [PMID:20418969] Source: Regenstrief LOINC

Basic Part Properties

Clostridium botulinum toxin A
Created On
Construct for LOINC Short Name
C bot Tox A

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Language Variants Get Info

zh-CNChinese (China)
肉毒梭菌毒素 A
Synonyms: 肉毒 A;肉毒 A 型;肉毒梭菌毒素 A 型;肉毒梭菌神经毒素 A;肉毒梭菌神经毒素 A 型;肉毒毒素 A;肉毒毒素 A 型
nl-NLDutch (Netherlands)
Clostridium botulinum toxine A
et-EEEstonian (Estonia)
Clostridium botulinum toksiin A
fr-BEFrench (Belgium)
Toxine Clostridium botulinum A
Synonyms: Clostridium botulinum A. Toxine
fr-CAFrench (Canada)
Toxine Clostridium botulinum A
it-ITItalian (Italy)
Clostridium botulinum, tossina A
Synonyms: Tossina A di Clostridium botulinum
ru-RURussian (Russian Federation)
Clostridium botulinum токсин A
es-ESSpanish (Spain)
Toxina A del Clostridium botulinum
Synonyms: Botox
tr-TRTurkish (Turkey)
Clostridium botulinum toksin A