100973-7 Influenza virus A RNA [Presence] in Nose by NAA with non-probe detection

Part Descriptions

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A RNA
Property
PrThr
Time
Pt
System
Nose
Scale
Ord
Method
Non-probe.amp.tar

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.74
Last Updated
Version 2.82 (MIN)
Order vs. Observation
Both

Example Answer List LL6280-3

AnswerCodeScoreAnswer ID
Flu A positiveLA33547-3
Flu A negativeLA33548-1
Specimen unsatisfactory for evaluation Copyright http://snomed.info/sct ID:125154007 Specimen unsatisfactory for evaluation (finding)LA13548-5

Member of these Panels

LOINCLong Common Name
100972-9Influenza virus A and Influenza virus B and SARS coronavirus 2 RNA panel - Nose by NAA with non-probe detection

Member of these Groups Get Info

LOINC GroupGroup Name
LG32757-3Influenza virus
LG34064-2Influenza virus A RNA|PrThr|Sys:ANYResp

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus chřipky A RNA:Přítomnost nebo práh:Časový bod:Nos:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
de-DEGerman (Germany)Influenza-Virus A RNA:Nachweis oder Schwellenwert:Zeitpunkt:Nase:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
el-GRGreek (Greece)Ιός γρίπης A RNA:PrThr:Pt:Μύτη:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου
Synonyms: A MICRO Ord PrThr Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός γρίπης Ιός γρίπης A Μύτη Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ESSpanish (Spain)Virus Influenza A RNA:PrThr:Punto temporal:Nariz:Ord:Amplificación del objetivo no basado en sonda
fr-CAFrench (Canada)Virus de l'influenza A ARN:Présence-Seuil:Temps ponctuel:Nez:Ordinal:Non-sonde.amplification de cible
fr-FRFrench (France)Influenza virus A ARN:Présence/Seuil:Ponctuel:Nez:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)Influenza A, virus RNA:PrThr:Pt:Naso:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A
pl-PLPolish (Poland)Wirus grypy A RNA:granica wykrywalności:punkt w czasie:nos:uporządkowany:bez sondy.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA wirusa grypy typu A Wirus grypy typ A
zh-CNChinese (China)流感病毒 A 型 RNA:存在情况或阈值:时间点:鼻:序数型:非探针法.基因扩增.靶向
Synonyms: A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒 RNA FLUA RNA FLUAV RNA FLUV;Influ;列性感冒病毒;流行性感冒病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 流感病毒甲型 RNA 甲型流感病毒 RNA 经过扩增的 脱氧核糖核酸探针 鼻部

100974-5 Influenza virus B RNA [Presence] in Nose by NAA with non-probe detection

Part Descriptions

LP14240-3   Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. PMID: 25812763 [CDC:flu/about/viruses/types] Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus B RNA
Property
PrThr
Time
Pt
System
Nose
Scale
Ord
Method
Non-probe.amp.tar

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.74
Last Updated
Version 2.82 (MIN)
Order vs. Observation
Both

Example Answer List LL6281-1

AnswerCodeScoreAnswer ID
Flu B positiveLA33549-9
Flu B negativeLA33550-7
Specimen unsatisfactory for evaluation Copyright http://snomed.info/sct ID:125154007 Specimen unsatisfactory for evaluation (finding)LA13548-5

Member of these Panels

LOINCLong Common Name
100972-9Influenza virus A and Influenza virus B and SARS coronavirus 2 RNA panel - Nose by NAA with non-probe detection

Member of these Groups Get Info

LOINC GroupGroup Name
LG32757-3Influenza virus
LG34065-9Influenza virus B RNA|PrThr|Sys:ANYResp

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus chřipky B RNA:Přítomnost nebo práh:Časový bod:Nos:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
de-DEGerman (Germany)Influenza-Virus B RNA:Nachweis oder Schwellenwert:Zeitpunkt:Nase:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
el-GRGreek (Greece)Ιός γρίπης B RNA:PrThr:Pt:Μύτη:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου
Synonyms: B MICRO Ord PrThr Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός γρίπης Ιός γρίπης B Μύτη Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ESSpanish (Spain)Virus Influenza B RNA:PrThr:Punto temporal:Nariz:Ord:Amplificación del objetivo no basado en sonda
fr-CAFrench (Canada)Virus de l'influenza B ARN:Présence-Seuil:Temps ponctuel:Nez:Ordinal:Non-sonde.amplification de cible
fr-FRFrench (France)Influenza virus B ARN:Présence/Seuil:Ponctuel:Nez:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)Influenza B, virus RNA:PrThr:Pt:Naso:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza B
pl-PLPolish (Poland)Influenza wirus B RNA:granica wykrywalności:punkt w czasie:nos:uporządkowany:bez sondy.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA wirusa grypy typu B Wirus grypy typu B
zh-CNChinese (China)流感病毒 B 型 RNA:存在情况或阈值:时间点:鼻:序数型:非探针法.基因扩增.靶向
Synonyms: B 型 B 型流感;B 型流感病毒;FLUB;FLUBV;乙型流感;乙型流感病毒;流感 B;流感 B 型;流感乙型;流感病毒乙型 B 型流感病毒 RNA FLUB RNA FLUBV RNA FLUV;Influ;列性感冒病毒;流行性感冒病毒 乙型流感病毒 RNA 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 流感病毒乙型 RNA 经过扩增的 脱氧核糖核酸探针 鼻部

96986-5 SARS-CoV-2 (COVID-19) N gene [Presence] in Nose by NAA with non-probe detection

Term Description

Qualitative of nucleic acids within the nucleoprotein (N) gene of SARS coronavirus 2 (SARS-CoV-2) in nasal specimens by nucleic acid amplification with non-probe based detection, such as melt curve analysis. Testing is performed for the diagnosis of Coronavirus Disease 2019 (COVID-19).

Part Descriptions

LP417599-0   SARS coronavirus 2 N gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov]https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance Source: Regenstrief LOINC

Fully-Specified Name

Component
SARS coronavirus 2 N gene
Property
PrThr
Time
Pt
System
Nose
Scale
Ord
Method
Non-probe.amp.tar

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.82 (MIN)
Order vs. Observation
Both

Example Answer List LL6282-9

AnswerCodeScoreAnswer ID
COVID-19 positiveLA33551-5
COVID-19 negativeLA33552-3
Specimen unsatisfactory for evaluation Copyright http://snomed.info/sct ID:125154007 Specimen unsatisfactory for evaluation (finding)LA13548-5

Member of these Panels

LOINCLong Common Name
100972-9Influenza virus A and Influenza virus B and SARS coronavirus 2 RNA panel - Nose by NAA with non-probe detection

Member of these Groups Get Info

LOINC GroupGroup Name
LG51004-6SARS coronavirus 2 N gene|PrThr|Sys:ANYResp
LG51017-8SARSCoV2 detection
LG51019-4SARSCoV2 molecular detection

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)SARS-CoV-2 (COVID-19) gen N:Přítomnost nebo práh:Časový bod:Nos:Ordinální:Amplifikace nukleových kyselin s detekcí bez sondy
de-DEGerman (Germany)SARS-Coronavirus 2 N-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Nase:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde
el-GRGreek (Greece)Γονίδιο Ν κορωνοϊού SARS 2:PrThr:Pt:Μύτη:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου
Synonyms: MICRO N Ord PrThr Pt Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Γονίδιο Γονίδιο Ν κορωνοϊού SARS 2 Κορωνοϊός Κορωνοϊός SARS Κορωνοϊός SARS 2 Μύτη Χωρίς ανιχνευτή.ενίσχυση.στόχου
es-ESSpanish (Spain)Gen N de SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Nariz:Ord:Amplificación del objetivo no basado en sonda
es-MXSpanish (Mexico)Gen del coronavirus 2 N del SARS:PrThr:Punto temporal:Nariz:Ordinal:Non-probe.amp.tar
fr-CAFrench (Canada)Gène N du coronavirus 2 du SRAS:Présence-Seuil:Temps ponctuel:Nez:Ordinal:Non-sonde.amplification de cible
fr-FRFrench (France)Coronavirus SARS-CoV-2 gène N:Présence/Seuil:Ponctuel:Nez:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)SARS coronavirus 2, gene N:PrThr:Pt:Naso:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Coronavirus della SARS Gene N di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
pl-PLPolish (Poland)Gen N SARS-CoV-2 (COVID-19):granica wykrywalności:punkt w czasie:nos:uporządkowany:bez sondy.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją bez użycia sondy amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Koronawirus
zh-CNChinese (China)SARS 冠状病毒 2 N 基因:存在情况或阈值:时间点:鼻:序数型:非探针法.基因扩增.靶向
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II N 型 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针 遗传基因;遗传因子;吉恩;生物基因 鼻部