Version 2.78

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LP411415-5   4-Fluorofentanyl
The compounds known as novel synthetic opioids (NSOs) have been emerging as drugs of abuse, given that many share pharmacological properties with common opioid agonists, yet they are difficult to detect and control. Since the early 2010s clandestine manufacturing of both novel fentanyl derivatives as well as other synthetic opioids has increased, with the list growing to upwards of more than 30 unique compounds. The list includes fentanyl analogs such as acetylfentanyl, butyrfentanyl, 4-methoxybutyrylfentanyl, 4-methylphenethylacetylfentanyl, furanylfentanyl, carfentanil (and its major metabolite norcarfentanil), ocfentanil, acrylfentanyl, 3-methylfentanyl and 4-fluorobutyrylfentanyl. Also, in the same category are non-fentanyl derived chemicals having opioid agonist activity such as AH-7921 and U47700(benzoamides) and MT-45 (a piperazine). The pharmacologic receptor profile of some predict that they would be highly addictive and in some cases much more potent (for example, 3-Methylfentanyl is about 1000 times and carfentanil may be 10,000 times more potent than morphine). The fact that they are often cut into heroin preparations or sold as counterfeit pain killers with users unaware of their content makes them particularly prone to overdose. The DEA has reported that the fentanyl crisis in the United States in the late 2010s has been largely fueled by NSOs PMID: 30634521. Source: Regenstrief LOINC

Fully-Specified Name

Component
4-Fluorofentanyl/Creatinine
Property
MRto
Time
Pt
System
Urine
Scale
Qn
Method
Confirm

Additional Names

Short Name
4-Fluorofentanyl/Creat Ur Cfm
Display Name
4-Fluorofentanyl/Creatinine Confirm (U) [Mass ratio]
Consumer Name Alpha Get Info
4-Fluorofentanyl/Creatinine, Urine

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.74
Last Updated
Version 2.75
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) 4-fluorofentenilo/Creatinina:Relacion de Masa:Punto temporal:Orina:Qn:Confirmatorio
Synonyms: Cuantitativo parafluorofentanilo
fr-FR French (France) 4-fluorofentanyl/créatinine:Masse ratio:Ponctuel:Urine:Numérique:Confirmation
it-IT Italian (Italy) 4-Fluorofentanyl/Creatinina:MRto:Pt:Urine:Qn:Conferma
Synonyms: Livelli farmacologici e tossicologia Parafluorofentanil Punto nel tempo (episodio) Rapporto di Massa
zh-CN Chinese (China) 4-氟芬太尼/肌酐:质量比率:时间点:尿液:定量型:毒理学确认试验
Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 UCr 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 来自于同一体系的两种分析物的质量之比;质量比 毒品 毒品类 确认方法;确认法;确认试验 肌酸内酰胺 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101161-8