101317-6
17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma --30 minutes post dose corticotropin
Active
Part Descriptions
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent.
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Source: Wikipedia, 17-hydroxypregnenolone (Wikipedia)
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 [Lab Tests Online:6-17hydroxy/tab/sample]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 17-Hydroxypregnenolone^30M post dose corticotropin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 17OH-Preg 30M p ACTH SerPl-mCnc
- Display Name
- 17-Hydroxypregnenolone 30 Min post dose corticotropin [Mass/Vol]
- Consumer Name Alpha Get Info
- 17-Hydroxypregnenolone 30 min after Corticotropin, Blood
Basic Attributes
- Class
- CHAL
- Type
- Laboratory
- First Released
- Version 2.74
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
101314-3 | 17-Hydroxypregnenolone and 17-Hydroxyprogesterone p corticotropin stim panel - Serum or Plasma |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | 17-Hidroxipregnenolona^30 minutos pos dosis de corticotropina: Synonyms: Cuantitativo |
fr-CA | French (Canada) | 17-hydroxyprégnénolone^30 min post dose hormone adrénocorticotrope: |
fr-BE | French (Belgium) | 17-hydroxyprégnénolone^30 min post dose hormone adrénocorticotrope: Synonyms: 30 min post dose ACTH ACTH Post dose. 30 min |
fr-FR | French (France) | 17-hydroxyprégnénolone T30min après synacthène: |
it-IT | Italian (Italy) | 17-Idrossipregnenolone^30Minuti post dose corticotropina: Synonyms: 30 minuti dopo dose 30 minuti dopo stimolo con corticotropina Concentrazione di Massa dopo dose dopo dose di corticotropina Plasma Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione |
nl-NL | Dutch (Netherlands) | 17-hydroxypregnenolon^30 min na dosis ACTH: Synonyms: 30M na dosis 30M na dosis ACTH adrenocorticotroop hormoon; |
ru-RU | Russian (Russian Federation) | 17-Гидроксипрегненолон^30 минут после дозы кортикотропина: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | 17-Hidroksipregnenolon^30dk snr kortikotropin dozu: |
zh-CN | Chinese (China) | 17-羟基孕烯醇酮^在给予剂量促肾上腺皮质激素之后30分钟: Synonyms: 0.5Hr之后于剂量物质; |
Example Units
Unit | Source |
---|---|
ng/dL | Example UCUM Units |
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